Important role for activation of a membrane switch in immunity
Innate immune responses serve as rapid defence against pathogenic agents. In this context, specialised macrophages play an important role, which kill and break down the pathogen in vesicles within cells. The mechanism of these processes and how they are controlled has so far only partly been understood.
Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent.
Annual Report 2015/16 of the Paul-Ehrlich-Institut published
Biomedicines are undergoing a rapid development – this is accompanied by the scientific and regulatory activities of the Paul-Ehrlich-Institut as a leading medicines authority in Europe. The Annual Report 2015/16 provides information on the strategy, marketing authorisation, testing and current research activities at the PEI in a national, European, and world-wide setting.