Paul-Ehrlich-Institut

Publikationen aus 1996

Autorinnen und Autoren des Paul-Ehrlich-Instituts sind durch Fettdruck kenntlich gemacht. Wenn Online-Abstracts oder Volltexte zu den Publikationen verfügbar sind, so sind diese verlinkt.

Arden B, Weber-Arden J, Wilbert O, Kabelitz D (1996): Preferential usage of the proximal cluster of duplicated Va gene segments in gd thymocytes.
Immunobiol. 196: 308.

Axelsen N H J, Kroll B (1996): Weeke Quantitative Immuno-electrophoresis, Methods and Applications.
Scandinavian Journal of Immunology 2: 1973.

Badenhoop K, Tönjes RR, Rau H, Donner H, Rieker W, Braun J, Herwig J, Mytilineos J, Kurth R, Usadel KH (1996): Endogenous retroviral long terminal repeats of the HLA-DQ region are associated with susceptibility to insulin-dependent diabetes mellitus.
Human Immunology 50: 103–110.

Bannert N, Baier M, Werner A, Kurth R (1996): Interleukin-16 or not.
Nature 381: 30.
Online-Abstract

Beer B, Norley S, Cichutek K, Kurth R (1996): Control of Initial Viraemia Coincides with Neutralizing Antibody Response after SIVmac Infection of Rhesus Macaques.
AIDS 10: 681-682.

Beer B, Scherer J, zur Megede J, Norley S, Baier M, Kurth R (1996): Lack of Dichotomy between Virus Load of Peripheral Blood and Lymph Nodes during Long-Term Simian Immunodeficieny Virus Infection of African Green Monkeys.
Virology 219: 367-375.
Online-Abstract

Bornhak H, Chudy M, Köstermenke M, Nick S, Schilow W, Soboll H, Unger G, Löwer J (1996): Sensitivity of HBsAg Assays Determined by Standard Preparations, Seroconversion Panels and Low Titer Samples. IX Triennial International Symposium on Viral Hepatitis and Liver Disease; Rome, Italy, April 21–25 1996.
Abstract 132.

Brown F, Cußler K, Hendriksen CFM (1996): Replacement, Reduction and Refinement of Animal Experiments in the Development and Control of Biological Products.
Dev. Biol. Standard 86.

Chudy M, Nübling CM, Scheiblauer H, Willkommen H, Löwer J (1996): Virusübertragung durch Blutprodukte: Mögliche Ursachen und Konsequenzen. Antwort auf den Leserbrief von D.L. Tankersley.
Hämostaseologie 16: 52-54.

Chudy M, Weeke-Lüttmann M, Löwer J (1996): Hepatitis B virus polymerase chain reaction: A possible alternative method to the in vivo assay using chimpanzees.
Developm. Biol. Stand. 86: 328.

Denner J (1996): Theoretische und klinische Grundlagen für eine ex vivo - Immunadsorptions-Therapie während der HIV-1 Infektion.
Infektionsepidemiologische Forschung.

Denner J, Norley S, Kurth R (1996): Das vom transmembranen Hüllprotein gp41 von HIV abgeleitete Immunsuppressive Peptid (ISU-Peptid) hemmt T- und B-Lymphozyten des Menschen.
Infektionsepidemiologische Forschung.

Denner J, Persin C, Vogel T, Haustein D, Norley S, Kurth R (1996): The Immunosuppressive Peptide of HIV-1 Inhibits T and B Lymphocyte Stimulation.
JAIDS 12: 442-450.
Online-Abstract

Denner J, Phelps RC, Kurth R (1996): Keine Aktivierung des humanen endogenen Retrovirus HERV-K in menschlichen Lymphozyten nach HIV-1 Infektion in vitro.
Infektionsepidemiologische Forschung.

Dittmar MT, Wagener S, Fultz P, Kurth R, Cichutek K (1996): An in vitro assay for the acute pathogenicity of immunodeficiency viruses.
Dev. Biol. Stand. 88: 167-174.

Dobmeyer TS, Dobmeyer JM, Klein SA, Helm EB, Hoelzer D, Kabelitz D, Rossol R (1996): BCL-2 expression is diminished in CD4+ lymphocytes of HIV infected patients.
Brit. J. Haematol. 93: 308.

Dobmeyer TS, Dobmeyer JM, Klein SA, Ottmann O, Helm EB, Hoelzer D, Kabelitz D (1996): IL-2 and IL-15 synergize in activating gd T cells: role for dyshematopoiesis in HIV infection.
Brit. J. Haematol. 93: 159.

Dobmeyer TS, Dobmeyer JM, Klein SA, Ottmann O, Helm EB, Hoelzer D, Rossol R, Kabelitz D (1996): gd T cells mediate myelosuppression in HIV infection.
Immunobiol. 196: 155.

Dobmeyer JM, Klein SA, Dobmeyer TS, Rossol S, Wesch D, Hoelzer D, Helm EB, Rossol R, Kabelitz D (1996): Increase of Vd1+ gd T cells in the peripheral blood and bone marrow as as selective feature of HIV-1 but not other viral infections: Resistance to TNF-a induced apoptosis as a possible mechanism.
Immunobiol. 196: 156.

Dodt J, Otte M, Friedrich T, Strube KH (1996): Thrombin inhibitors of blood sucking animals.
Sem. Thromb. Hemost. 22: 203-208.

Ebert E, Kusch M, Öppling V, Werner E, Cussler K (1996): Serologische Wirksamkeitsprüfung von Clostridium perfringensbetatoxoidhaltigen Veterinärimpfstoffen - eine Alternative zum gesetzlich vorgeschriebenen Mäuseneutralisationstest.
ALTEX 13: 65-75.
Online-Abstract

Ebert E, Öppling V, Werner E, Cussler K (1996): Qualification of antibodies against Clostridium perfringens type C beta toxin by ELISA as an alternative to the mouse neutralization assay for potency testing of horse hyperimmune sera.
ATLA 24: 315.

Egbring R, Kröniger A, Seitz R (1996): Erworbene Inhibitoren gegen Faktor XIII.
Hämostaseologie 16: 174-179.

Egbring R, Kröniger A, Seitz R (1996): Factor XIII deficiency Pathogenic mechanisms and clinical significance.
Semin Thromb Hemost 22: 419-425.

Fischer S, Scheffler A, Kabelitz D (1996): Reaktivität von T-Lymphozyten gegen Mistel-Inhaltsstoffe.
Forsch. Komplementärmed. 3: 16.

Fischer S, Scheffler A, Kabelitz D (1996): Activation of human gd T-cells by heat-treated plant extracts.
Immunol. Letters 52: 69-72.
Online-Abstract

Hartinger J, Stenius K, Högemann D, Jahn R (1996): 16-BAC/SDS-PAGE : A two-dimensional gel electrophoresis system suitable for the separation of integral membrane proteins.
Anal. Biochem 240: 126-133.
Online-Abstract

Heiden M, Seitz R, Egbring R (1996): The role of inflammatory cells and their proteases in extravascular fibrinolysis.
Semin Thromb Hemost 22: 497-501.
Online-Abstract

Heinmöller E, Weinel RJ, Heidtmann HH, Salge U, Seitz R, Schmitz I, Müller KM, Zirngibl H (1996): Studies on tumor-cell-induced platelet aggregation in human lung cancer cell lines.
J Cancer Res Clin Oncol 122: 735-744.

Hinz T, Dobmeyer T, Mentzel U, Marx S, Böhme A, Arden B, Rossol R, Hoelzer D, Kabelitz D (1996): Clonal expansion of Vg3/Vd3-expressing T-cells in a HIV-1/2-negative patient with CD4 T cell deficiency.
Immunobiol. 196: 159.

Hinz T, Marx S, Nerl C, Kabelitz D (1996): Clonal expansion of gd T cells expressing two distinct T cell receptors.
Brit. J. Haematol. 94: 62-64.

Jankiewicz A, Aulepp H, Baltes W, Bögl KW, Dehne LI, Zuberbier T, Vieths S (1996): Allergic sensitization to native and heated celery root in pollen-sensitive patients investigated by skin test and IgE binding.
Int Arch Allergy Immunol 111: 268-278.
Online-Abstract

Janssen O, Lengl-Janßen B, Oberg HH, Robertson M, Kabelitz D (1996): Induction of cell death via Fas (CD95, Apo-1) may be associated with but is not dependent on Fas-induced tyrosine phosphorylation.
Immunol. Letters 49: 63-69.
Online-Abstract

Jin M, Ido E, Kuwata T, Igarashi T, Cichutek K, Kurth R, Miura T, Enose Y, Chen J, Hayami M (1996): Replication and cytopathogenicity of HIV-1/SIVagm3 chimeric viruses in human and monkey cells: The 5´-half of the HIV-1 genome is responsible for the viral cytopathogenicity.
J. Gen.Virol. 77: 2427-2431.
Online-Abstract

Jungbäck C, Lemke I (1996): Die Wirksamkeit von Impfstoffen und Faktoren, die diese negativ beeinflussen können.
Der praktische Tierarzt 1: 6-8.

Kabelitz D, Marx S, Robertson MJ, Janssen O (1996): Rapid modulation of T lymphocyte surface antigens induced by Fas (CD95, APO-1) ligation.
Cell. Immunol. 173: 108-115.
Online-Abstract

Kabelitz D (1996): Impfempfehlungen für Kinder, Jugendliche und Erwachsene.
Pharmaz. Zeitung 141: 2381-2386.

Klausmann G, Ostermann EV, Seitz R, Herz R (1996): Opposite variations of fibrinogen (Fib) plasma levels in overweight type II diabetics and non-diabetics during weight loss. Third Int. Fibrinogen Sympos. Hemostasis, Inflammation and Cardiovascular Disease.
Fibrinolysis 10: 15.
Online-Abstract

Klein SA, Dobmeyer JM, Dobmeyer TS, Falke D, Kabelitz D, Friese K, Helm EB, Hoelzer D, Rossol-Voth R (1996): TNF-a mediated apoptosis of CD4 positive T-lymphocytes. A model of T-cell depletion in HIV infected individuals.
Eur. J. Med. Res. 1: 249-258.
Online-Abstract

Klein H, Mehlhorn H, Rüger W (1996): In vitro biosynthesis and in vivo processing of the major microneme antigen of Sarcocystis muris cyst merozoites.
Parasitol.Res. 82: 468-474.
Online-Abstract

Klein H, Mehlhorn H, Rüger W (1996): Characterization of genomic clones encoding two microneme antigens of Sarcocystis muris (Apikomplexa).
Parsitol.Res. 82: 230-237.
Online-Abstract

Krämer B, Nagel M, Duchow K, Schwanig M, Cußler K (1996): Ist die tierexperimentelle Prüfung auf anomale Toxizität für Impfstoffe, Sera und Immunglobuline noch zeitgemäß?.
ALTEX 13: 7-16.
Online-Abstract

Kurth R, Norley S (1996): Why don't the natural hosts of SIV develop AIDS?.
Journal of NIH Research 8: 33-37.

Kurth R (1996): HIV-Vermehrung - Entdeckung natürlicher Botenstoffe mit Hemmwirkung.
Spektrum der Wissenschaft 6: 22-24.
Online-Abstract

Lengl-Janßen B, Kamradt T, Steere AC, Janssen O, Kabelitz D (1996): Preferential stimulation of gd T cells expressing Vd1 by Borrelia burgdorferi antigens.
Immunobiol. 196.

Löwer J (1996): Rückkehr zur Normalität: HIV repliziert und infiziert wie ein gewöhnliches Virus.
AIDS-Forschung 11: 75-78.

Löwer J (1996): Creutzfeldt-Jakob-Erkrankung: Zur Diskussion um das Risiko einer Übertragung durch Blut und Blutprodukte.
Bundesgesundheitsblatt 39: 284-289.

Löwer J (1996): Risk assessment and limitations of evaluation studies.
Developments in Biological Standardization 88: 109.

Löwer J (1996): Viren in Blut und Blutprodukten: Strategien zur Verhütung ihrer Übertragung.
Hämophilie-Blätter: 47-51.

Löwer R, Löwer J, Kurth R (1996): The viruses in all of us: Characteristics and biological significance of human endogenous retrovirus sequences.
PNAS 93: 5177-5184.
Online-Abstract

Lüderitz-Püchel U, May S, Haustein D (1996): Zwischenfälle nach Hyposensibilisierung.
MMW Münchner Medizinische Wochenschrift 138: 129-132.

Lüke W, Coulibaly C, Dittmer U, Voss G, Oesterle R, Makoschey B, Sauermann U, Jurkiewicz E, Stahl-Henning C, Petry H, Hunsmann G (1996): Simian Immunodeficiency Virus (SIV) gp130 Oligomers Protect Rhesus Macaques (Macaca mulatta) against the Infection with SIVmac32H Grown on T-Cells or Derived ex Vivo.
Virology 216: 444-450.
Online-Abstract

Lugert R, König H, Kurth R, Tönjes R (1996): Specific Suppression of False Positive Signals in the Product-Enhanced Reverse Transcriptase Assay.
Biotechniques 20: 210-217.
Online-Abstract

Merget-Millitzer H, Müller P, Engelstädter M, Wagener S, Cichutek K (1996): HIV and AIDS: Implications of the genetic variability of HIV for pathogenesis and epidemiology.
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Mikkola H, Yee V, Syrjälä M, Seitz R, Egbring R, Petrini P, Ljung R, Ingerslev J, Teller D, Peltonen L, Palotie A (1996): Four novel mutations in deficiency of coagulation Factor XIII: consequences to expression and structure of the A-subunit.
Blood 87: 141-151.
Online-Abstract

Montag Th, König H, Grundmann C, Schmitt K, Seitz R, Schramm W (1996): Quality Control of Prothrombin Complex Preparations.
Annals of Hematology 72: A 79.

Moos M: Das NURMI-Konzept: Eine unspezifische Salmonellosebekämpfung und ihre arzneimittelrechtliche Problematik.
In: Berichtsband der Deutschen Veterinärmedizinischen Gesellschaft (DVG) zur Tagung in Rauischholzhausen, 12.-14. Juni 1996., 1996. 125-129.

Moos M, Mainka C: Impfmaßnahmen zur Zoonosenprophylaxe in der Humanmedizin unter besonderer Berücksichtigung der Tollwutbekämpfung.
In: Berichtsband der Deutschen Veterinärmedizinischen Gesellschaft (DVG) zum 6. Hohenheimer Seminar, Stuttgart-Hohenheim, 23.–24. September 1996., 1996. 195-204.

Norley S, Beer B, Binninger-Schinzel D, Vogel T, Siegel F, Cosma C, König H, zur Megede J, Kurth R (1996): Simian immunodeficiency virus live and inactivated experimental vaccines.
AIDS Research and Human Retrovirus 12: 447-449.

Norley S, Beer B, Binninger-Schinzel D, Cosma C, Kurth R (1996): Protection from pathogenic SIVmac challenge following short-term infection with a nef-deficient attenuated virus.
Virology 219: 195-205.
Online-Abstract

Norley S (1996): SIVagm infection of its natural African green monkey host.
Immunol. Let. 51: 53-58.
Online-Abstract

Norley S, Kurth R (1996): AIDS Vaccination.
Concepts in Vaccine Development: 553-558.

Norley S, Kurth R (1996): Simian immunodeficiency virus as a model of HIV pathogenesis. Immunopathogenesis of HIV infection.
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Nübling CM, Chudy M, Löwer J (1996): Virus testing of plasma pools and blood products by nucleic acid amplification.
Hämostaseologie 16: 274-276.

Nübling CM, Löwer J (1996): Presence of GB-C genomes in a potential high risk group, in plasma pools and in intravenous immunoglobulins ("letter to the editor").
The Lancet 347: 68.
Online-Abstract

Oberg HH, Lengl-Janssen D, Kabelitz D, Janssen O (1996): Activation-induced T cell death: susceptibility or resistance of individual T cell clones do not correlate to tyrosine phosphorylatin or Fas-L mRNA expression.
Immunobiol. 196: 46-47.

Oberg HH, Pohl T, Wesch D, Marx S, Janssen O, Kabelitz D (1996): Effect of anti-cytokine-receptor workshop antibodies on activation-induced death of T-lymphocytes.
Tissue Antigens 48: 403.

Oberg HH, Wesch D, Marx S, Pohl T, Janssen O, Kabelitz D (1996): Effect of anti-T-cell workshop antibodies on activation-induced death of T-lymphocytes.
Tissue Antigens 48: 482.

Öppling V, Kusch M, Rübmann P, Cussler K (1996): Serological Potency Testing of Vaccines Against Progressive Atrophic Rhinitis Posterabstract.
Dev. Biol. Stand. 86: 339.

Petersen A, Vieths S, Aulepp H, Schlaak M, Becker WM (1996): Ubiquitous structures responsible for IgE cross-reactivity between tomato fruit and grass pollen allergens.
J Allergy Clin Immunol 98: 805-815.
Online-Abstract

Rommel M, Tenter AM, Horn K, Daugschies A, Mertens C, Heydorn AO, Entzeroth R, Eschenbacher KH, Klein, H (1996).
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Sanzenbacher R, Kabelitz D, Janssen O (1996): Further analysis of p59fyn(T) and p56lck-SH3-binding proteins in T cell lines.
Immunobiol. 196: 215.

Scheiblauer H, Nübling M, Willkommen H, Löwer J (1996): The Prevalence of Hepatitis C Virus in Plasma Pools and the Effectiveness of Cold Ethanol Fractionation.
Clinical Therapeutics 18: 59-70.
Online-Abstract

Schöning B, Ziegler WH, Vieths S, Baltes W (1996): Apple allergy: The cDNA sequence determined by performing PCR with a primer based on the N-terminal amino acid sequence of the major allergen of apple is highly homologous to the sequence of the major birch pollen allergen.
J Sci Food Agric 71: 475-482.

Schwanig M, Esteban M, Ghislain C, Grandjean Y, Jepsen S, Roumiantzeff M (1996): Models for scientific and economic interaction in vaccine R & D. European Commission COST/STD Initiative.
report of expertt panel I Vaccine 14: 582-610.

Seitz R, Duckert F, Lopaciuk S, Muszbek L, Rodeghiero F, Seligsohn U (1996): ETRO Working Party on Factor XIII Questionnaire on Congenital Factor XIII Deficiency in Europe: Status and Perspectives.
Semin Thromb Hemost 22: 415-418.
Online-Abstract

Seitz R, McDonagh J, Egbring R (1996): Factor XIII: State of the art 1996.
Semin Thromb Hemost 22.

Seitz R, Montag-Lessing Th (1996): Lieferprobleme bei Humanalbumin: Paul-Ehrlich-Institut unschuldig.
Dtsch Apoth Ztg 136: 1310.

Siegl G, Bornhak H, Gerlich W, Jahn G, Jilg W, Maurer W, Mertens Th, Neumann-Haefelin D, Pauli G, Popow-Kraupp Th, Reigel F, Zeichardt H (1996): Indikationen für den Einsatz der Nukleinsäureamplifikationstechniken in der virologischen Diagnostik.
Virus Spike: 1-7.

Simpson GR, Patience C, Löwer R, Tönjes RR, Moore H.D, Weiss R.A, Boyd M T (1996): Endogenous D-Type (HERV-K) related sequences are packaged into retroviral particles in the placenta and possess open reading frames for reverse transcriptase.
Virology 222: 451-456.
Online-Abstract

Sopper S, Demuth M, Stahl-Henning C, Hunsmann G, Plesker R, Coulibaly C, Czub S, Ceska M, Koutsilieri E, Riederer P., Brinkmann R, Katz M, ter Meulen V (1996): The Effect of Simian Immunodeficiency Virus Infection in Vitro and in Vivo on the Cytokine Production of Isolated Microglia and Peripheral Macrophages from Rhesus Monkey.
Virology 220: 320-329.
Online-Abstract

Tönjes R R, Löwer R, Boller K, Denner J, Hasenmaier B, Kirsch H, König H, Korbmacher C, Limbach C, Lugert R, Phelps RC, Scherer J, The-len K, Löwer J, Kurth R (1996): HERV-K: The biologically most active human endogenous retrovirus family.
Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology 13: 261-267.
Online-Abstract

Vieths S, Haustein D, Hoffmann A, Jankiewicz A, Schöning B (1996): Labile und stabile Allergene in Lebensmitteln pflanzlicher Herkunft. Nachweismethoden und molekulare Charakteristika.
GIT Fachz Lab: 360-367.

Vieths S, Jankiewicz A, Schöning B, Haustein D (1996): Profiline - ubiquitäre Proteine mit spezifischer physiologischer Funktion und potente Pflanzenallergene. Teil II: Signaltransduktion, Molekülstruktur und Allergenität.
Allergo J 5: 157-162.

Vieths S, Jankiewicz A, Schöning B, Haustein D (1996): Profiline - ubiquitäre Proteine mit spezifischer physiologischer Funktion und potente Pflanzenallergene. Teil I: Regulation der Aktinpolymerisation.
Allergo J 5: 89-92.

Vieths S (1996): Molekulare Grundlagen des "oralen Allergiesyndroms" bei Birkenpollenallergikern.
Lebensmittelchemie 50: 157-158.

Wagener S, Norley S, zur Megede J, Kurth R, Cichutek K (1996): Induction of antibodies against SIV antigens after intramuscular nucleic acid inoculation using complex expression constructs.
J. Biotechnol. 44: 59-65.
Online-Abstract

Weber-Arden J, Wilbert OM, Kabelitz D, Arden B (1996): Inverse PCR amplification of low-abundancy message of gd T-cell receptor genes.
J. Immunol. Meth. 197: 187-192.
Online-Abstract

Wellhausen A, Schöning B, Petersen A, Vieths S (1996): IgE binding to a new cross-reactive structure: a 35 kDa protein in birch pollen, exotic fruit and other plant foods.
Z Ernährungswiss 35: 348-355.

Wesch D, Kabelitz D, Friese K, Pechhold K (1996): Mycobacteria-reactive gd T cells in HIV-infected individuals: Lack of Vg9 cell responsiveness is due to deficiency of antigen-specific CD4 T helper 1 cells.
Eur. J. Immunol. 26: 557-562.
Online-Abstract

Wesch D, Marx S, Kabelitz D (1996): Differential effect of IL-10 and IL-12 on the in vitro reactivity of human gd T cells to killed mycobacteria and Daudi tumor cells.
Immunobiol. 196: 25.

Wilbert OM, Weber-Arden J, Kabelitz D, Arden B (1996): TCRd rearrange-ment in thymus development: implications for ab/gd lineage commitment.
Immunobiol. 196: 316-317.

Willkommen H, Löwer J (1996): Sicherheit von Blut und Blutprodukten - Erfahrungen und Konsequenzen.
Tagungsband des Symposiums der Salzburger Ärztegesellschaft.

Zott A (1996): Study 2: The use of IgY antibodies for the identification of pertussis antigens in DTpa vaccines by means of rocket immunoelectrophoresis.
ALTA.

Zott A, Schwanig M (1996): A proposal for the development of a standardised programme for the calculation of probit analysis.
Developments in Biological Stansdardization 86: 349.