Paul-Ehrlich-Institut

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Publikationen Prof. Dr. Isabelle Bekeredjian-Ding

Autorinnen und Autoren des Paul-Ehrlich-Instituts sind durch Fettdruck kenntlich gemacht. Wenn Online-Abstracts oder Volltexte zu den Publikationen verfügbar sind, so sind diese verlinkt.

Arrazuria R, Kerscher B, Huber KE, Hoover JL, Lundberg CV, Hansen JU, Sordello S, Renard S, Aranzana-Climent V, Hughes D, Gribbon P, Friberg LE, Bekeredjian-Ding I (2022): Expert workshop summary: Advancing toward a standardized murine model to evaluate treatments for antimicrobial resistance lung infections.
Front Microbiol 13: 988725.
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Arrazuria R, Kerscher B, Huber KE, Hoover JL, Lundberg CV, Hansen JU, Sordello S, Renard S, Aranzana-Climent V, Hughes D, Gribbon P, Friberg LE, Bekeredjian-Ding I (2022): Variability of murine bacterial pneumonia models used to evaluate antimicrobial agents.
Front Microbiol 13: 988728.
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Jepsen K, Falk W, Brune F, Cosgarea R, Fimmers R, Bekeredjian-Ding I, Jepsen S (2022): Prevalence and Antibiotic Susceptibility Trends of Selected Enterobacteriaceae, Enterococci, and Candida albicans in the Subgingival Microbiota of German Periodontitis Patients: A Retrospective Surveillance Study.
Antibiotics (Basel) 11: 385.
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Miranda-García MA, Hoffelner M, Stoll H, Ruhaltinger D, Cichutek K, Siedler A, Bekeredjian-Ding I (2022): A 5-year look-back at the notification and management of vaccine supply shortages in Germany.
Euro Surveill 27: 2100167.
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Wöhrle F, Kerscher B, Cicin-Sain L, Bekeredjian-Ding I (2022): DGfI Study Group Vaccines - Annual Meeting 2022.
Eur J Immunol 52: 370-371.
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Etna MP, Signorazzi A, Ricci D, Severa M, Rizzo F, Giacomini E, Gaggioli A, Bekeredjian-Ding I, Huckriede A, Coccia EM (2021): Human plasmacytoid dendritic cells at the crossroad of type I interferon-regulated B cell differentiation and antiviral response to tick-borne encephalitis virus.
PLoS Pathog 17: e1009505.
Online-Abstract

Jepsen K, Falk W, Brune F, Fimmers R, Jepsen S, Bekeredjian-Ding I (2021): Prevalence and antibiotic susceptibility trends of periodontal pathogens in the subgingival microbiota of German periodontitis patients: A retrospective surveillance study.
J Clin Periodontal 48: 1216-1227.
Online-Abstract

Kamp C, Becker B, Matheis W, Öppling V, Bekeredjian-Ding I (2021): How to draw the line - Raman spectroscopy as a tool for the assessment of biomedicines.
Biol Chem 402: 1001-1006.
Online-Abstract

Prax M, Spindler-Raffel E, McDonald CP, Bearne J, Satake M, Kozakai M, Rojo J, Hanschmann KO, Lambrecht B, Grundmann U, O'Flaherty N, Klimek A, Bekeredjian-Ding I, Gathof BS, Störmer M, Süßner S, Renke C, Lee CK, Knabbe C, Volllmer T, Keil SD, Shipps ME, Wagner SJ, Jentsch U, Mpumlwana X, Cloutier M, Bringmann P, Lu T, Ramirez-Arcos S, Kou Y, Krut O, ISBT Transfusion-Transmitted Infectious Diseases Working Party, Subgroup on Bacteria (2021): Establishment of Transfusion-Relevant Bacteria Reference Strains for Red Blood Cells.
Vox Sang 116: 692-701.
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Ticha O, Moos L, Bekeredjian-Ding I (2021): Effects of long-term cryopreservation of PBMC on recovery of B cell subpopulations.
J Immunol Methods 495: 113081.
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Ticha O, Slanina P, Moos L, Stichova J, Vlkova M, Bekeredjian-Ding I (2021): TNFR2 expression is a hallmark of human memory B cells with suppressive function.
Eur J Immunol 51.
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Bekeredjian-Ding I, van Molle W, Baay M, Neels P, PEI speakers and session chairs (2020): Human challenge trial workshop: Focus on quality requirements for challenge agents, Langen, Germany, October 22, 2019.
Biologicals 66: 53-61.
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Goeser F, Münch P, Lesker TR, Lutz PL, Krämer B, Kaczmarek DJ, Finnemann C, Nischalke HD, Geffers R, Parcina M, McHardy A, Strassburg C, Hoerauf A, Nattermann J, Bekeredjian-Ding I, Spengler U (2020): Neither Black Nor White: Do Altered Intestinal Microbiota Reflect Chronic Liver Disease Severity?.
Gut 70: 438-440.
Online-Abstract

Loessner H, Schlattmeier I, Anders-Maurer M, Bekeredjian-Ding I, Rohde C, Wittmann J, Pokalyuk C, Krut O, Kamp C (2020): Kinetic Fingerprinting Links Bacteria-Phage Interactions with Emergent Dynamics: Rapid Depletion of Klebsiella pneumoniae Indicates Phage Synergy.
Antibiotics (Basel) 9: 408.
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Uebele J, Habenicht K, Ticha O, Bekeredjian-Ding I (2020): Staphylococcus aureus Protein A Induces Human Regulatory T Cells Through Interaction With Antigen-Presenting Cells.
Front Immunol 11: 581713.
Online-Abstract

Bekeredjian-Ding I, Pletz MW (2019): Impfung gegen endogene Infektionen mit Antibiotika-resistenten Bakterien.
Trillium Immunologie 3: 178-183.
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Götz K, Bekeredjian-Ding I: Immunprophylaxe gegen die Antibiotika-assoziierte Diarrhö.
In: Roeb E, Kempf VAJ (Hrsg.), Leitsymptom Diarrhö: De Gruyter, 2019. S. 277-302, ISBN 978-3-11-053753-6

Matheis W, Bekeredjian-Ding I (2019): Raman-Spektroskopie: 'Gefakte' Impfstoffe aufspüren.
Dtsch Arztebl 116: A2192-A3.
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Miller L, Klemm J, Schmidt C, KM Hanschmann, Bekeredjian-Ding I, Waibler Z (2019): Individual combinations of danger signals synergistically increase FVIII product immunogenicity.
Haemophilia 25: 996-1002.
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Prax M, Bekeredjian-Ding I, Krut O (2019): Microbiological Screening of Platelet Concentrates in Europe.
Transfus Med Hemother 46: 76-86.
Online-Abstract

Silge A, Matheis W, Becker B, Bocklitz T, Popp J, Bekeredjian-Ding I (2019): Raman-Spektroskopie zur Prüfung von Impfstoffen.
GIT Labor-Fachzeitschrift 63: 46-48.
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Trösemeier JH, Rudorf S, Loessner H, Hofner B, Reuter A, Schulenborg T, Koch I, Bekeredjian-Ding I, Lipowsky R, Kamp C (2019): Optimizing the dynamics of protein expression.
Sci Rep 9: 7511.
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Bekeredjian-Ding I (2018): Impfstoffentwicklung zur Prävention nosokomialer Infektionen.
Arzneiverordnung in der Praxis 45: 4-12.
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Froeschen F, Gajdiss M, Uebele J, Meilaender A, Hoerauf A, Exner M, Molitor E, Bierbaum G, Engelhart S, Bekeredjian-Ding I (2018): Rapid monitoring of vancomycin-resistant Enterococcus faecium in hospital departments by repetitive element palindromic polymerase chain reaction.
J Hosp Infect 99: 208-217.
Online-Abstract

Funk MB, Heiden M, Willkommen H, Aepfelbacher M, Bauerfeind U, Bekeredjian-Ding I, Blümel J, Burger R, Doll M, Gröner A, Gürtler L, Hildebrandt M, Jansen B, Offergeld R, Pauli G, Schlenkrich U, Schottstedt V, Seitz R, Stahl D, Strobel J (2018): Mitteilungen des Arbeitskreises Blut des Bundesministeriums für Gesundheit: Pathogen-Inaktivierungssysteme für Thrombozytenkonzentrate - Stellungnahme.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 61: 874-893.
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Kamp C, Blümel J, Baylis SA, Bekeredjian-Ding I, Chudy M, Heiden M, Henseler O, Keller-Stanislawski B, de Vos AS, Funk MB (2018): Impact of hepatitis E virus testing on the safety of blood components in Germany - results of a simulation study.
Vox Sang 113: 811-813.
Online-Abstract

Krut O, Bekeredjian-Ding I (2018): Contribution of the Immune Response to Phage Therapy.
J Immunol 200: 3037-3044.
Online-Abstract

Schett G, Bozec A, Bekeredjian-Ding I, Chang HD, David JP, Dörner T, Grässel S, Gunzer M, Manz R, Mei H, Mielenz D, Müller-Ladner U, Neumann E, Radbruch A, Richter W, Straub RH (2018): Neue Einblicke in die Funktion des Knochenmarks.
Z Rheumatol 77 (Suppl 1): 4-7.
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Silge A, Bocklitz T, Becker B, Matheis W, Popp J, Bekeredjian-Ding I (2018): Raman spectroscopy-based identification of toxoid vaccine products.
NPJ Vaccines 3:50.
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Ticha O, Moos L, Wajant H, Bekeredjian-Ding I (2018): Expression of Tumor Necrosis Factor Receptor 2 Characterizes TLR9-Driven Formation of Interleukin-10-Producing B Cells.
Front Immunol 8: Article 1951.
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Bekeredjian-Ding I (2017): Deciphering the significance of the T-cell response to Staphylococcus aureus.
Future Microbiol 12: 1023-1026.
Online-Abstract

Bekeredjian-Ding I, Stein C, Uebele J (2017): The Innate Immune Response Against Staphylococcus aureus.
Curr Top Microbiol Immunol 409: 385-418.
Online-Abstract

Domanović D, Cassini A, Bekeredjian-Ding I, Bokhorst A, Bouwknegt M, Facco G, Galea G, Grossi P, Jashari R, Jungbauer C, Marcelis J, Raluca-Siska I, Andersson-Vonrosen I, Suk JE (2017): Prioritizing of bacterial infections transmitted through substances of human origin in Europe.
Transfusion 57: 1311-1317.
Online-Abstract

Hirschfeld J, Akinoglu EM, Wirtz DC, Hoerauf A, Bekeredjian-Ding I, Jepsen S, Haddouti EM, Limmer A, Giersig M (2017): Long-term release of antibiotics by carbon nanotube-coated titanium alloy surfaces diminish biofilm formation by Staphylococcus epidermidis.
Nanomedicine 13: 1587-1593.
Online-Abstract

Hirschfeld J, Howait M, Movila A, Parčina M, Bekeredjian-Ding I, Deschner J, Jepsen S, Kawai T (2017): Assessment of the involvement of the macrophage migration inhibitory factor-glucocorticoid regulatory dyad in the expression of matrix metalloproteinase-2 during periodontitis.
Eur J Oral Sci 125: 345-354.
Online-Abstract

Mellmann A, Spindler-Raffel E, Bletz S, Prax M, Bekeredjian-Ding I (2017): Genome Sequences of the First WHO Repository of Platelet Transfusion-Relevant Bacterial Reference Strains.
Genome Announc 5: e00001-17.
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Miranda-Garcia MA, Cichutek K, Bekeredjian-Ding I (2017): Wie lange bleibt der Kühlschrank leer? Das Paul-Ehrlich-Institut analysierte die Lieferengpässe bei Reiseimpfstoffen.
Dtsch Apoth Ztg 157: 24-29.
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Miranda-Garcia MA, Götz KB, Ruhaltinger D, Cichutek K, Bekeredjian-Ding I (2017): Lieferengpässe von Impfstoffen: Einblick in Zahlen und Hintergründe.
Dtsch Arztebl 114: A-844 / B-714 / C-700.
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Spindler-Raffel E, Benjamin RJ, McDonald CP, Ramirez-Arcos S, Aplin K, Bekeredjian-Ding I, de Korte D, Gabriel C, Gathof B, Hanschmann KM, Hourfar K, Ingram C, Jacobs MR, Keil SD, Kou Y, Lambrecht B, Marcelis J, Mukhtar Z, Nagumo H, Niekerk T, Rojo J, Marschner S, Satake M, Seltsam A, Seifried E, Sharafat S, Störmer M, Süßner S, Wagner SJ, Yomtovian R for the ISBT Working Party Transfusion-Transmitted Infectious Diseases (WP-TTID) Subgroup on Bacteria (2017): Enlargement of the WHO international repository for platelet transfusion-relevant bacteria reference strains.
Vox Sang 112: 713-722.
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Uebele J, Stein C, Nguyen MT, Schneider A, Kleinert F, Tichá O, Bierbaum G, Götz F, Bekeredjian-Ding I (2017): Antigen delivery to dendritic cells shapes human CD4+ and CD8+ T cell memory responses to Staphylococcus aureus.
PLOS Pathog 13: e1006387.
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Bekeredjian-Ding I (2016): Lieferengpässe bei Impfstoffen - Meldungen, Gründe und Auswirkungen.
Bulletin zur Arzneimittelsicherheit 7: 30-36.
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El-Jade MR, Parcina M, Schmithausen RM, Stein C, Meilaender A, Hoerauf A, Molitor E, Bekeredjian-Ding I (2016): ESBL Detection: Comparison of a Commercially Available Chromogenic Test for Third Generation Cephalosporine Resistance and Automated Susceptibility Testing in Enterobactericeae.
PLOS ONE 11: e0160203.
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Fettke F, Schumacher A, Canellada A, Toledo N, Bekeredjian-Ding I, Bondt A, Wuhrer M, Costa SD, Zenclussen AC (2016): Maternal and Fetal Mechanisms of B Cell Regulation during Pregnancy: Human Chorionic Gonadotropin Stimulates B Cells to Produce IL-10 While Alpha-Fetoprotein Drives Them into Apoptosis.
Front Immunol 7: 495.
Online-Abstract

Hischebeth GT, Randau TM, Buhr JK, Wimmer MD, Hoerauf A, Molitor E, Bekeredjian-Ding I, Gravius S (2016): Unyvero i60 implant and tissue infection (ITI) multiplex PCR system in diagnosing periprosthetic joint infection.
J Microbiol Methods 121: 27-32.
Online-Abstract

Hischebeth GT, Randau TM, Molitor E, Wimmer MD, Hoerauf A, Bekeredjian-Ding I, Gravius S (2016): Comparison of bacterial growth in sonication fluid cultures with periprosthetic membranes and with cultures of biopsies for diagnosing periprosthetic joint infection.
Diagn Microbiol Infect Dis 84: 112-115.
Online-Abstract

Idelevich EA, Büsing M, Mischnik A, Kaase M, Bekeredjian-Ding I, Becker K (2016): False non-susceptible results of tigecycline susceptibility testing against Enterobacteriaceae by an automated system: a multicentre study.
J Med Microbiol 65: 877-881.
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Pauli G, Aepfelbacher M, Bauerfeind U, Bekeredjian-Ding I, Blümel J, Burger R, Funk M, Gröner A, Gürtler L, Heiden M, Hildebrandt M, Jansen B, Offergeld R, Schlenkrich U, Schottstedt V, Seitz R, Stahl D, Strobel J, Willkommen H (2016): Zika Virus (ZIKV).
Transfus Med Hemother 43: 436-446.
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Pletz MW, Uebele J, Götz K, Hagel S, Bekeredjian-Ding I (2016): Vaccines against major ICU pathogens: where do we stand?.
Curr Opin Crit Care 22: 470-476.
Online-Abstract

Waller T, Götz K, Spreitzer I, Bekeredjian-Ding I (2016): Immunmodulatorische Wirkung von Outer Membrane Vesicles - Stand der Forschung und Implikationen für die Arzneimittelsicherheit.
Bulletin zur Arzneimittelsicherheit 7: 30-34.
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Waller T, Kesper L, Hirschfeld J, Dommisch H, Kölpin J, Oldenburg J, Uebele J, Hoerauf A, Deschner J, Jepsen S, Bekeredjian-Ding I (2016): Porphyromonas gingivalis Outer Membrane Vesicles Induce Selective Tumor Necrosis Factor Tolerance in a Toll-Like Receptor 4- and mTOR-Dependent Manner.
Infect Immun 84: 1194-1204.
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Hirschfeld J, Dommisch H, Skora P, Horvath G, Latz E, Hoerauf A, Waller T, Kawai T, Jepsen S, Deschner J, Bekeredjian-Ding I (2015): Neutrophil extracellular trap formation in supragingival biofilms.
Int J Med Microbiol 305: 453-463.
Online-Abstract

Mayer K, Hahn-Ast C, Mückter S, Schmitz A, Krause S, Felder L, Bekeredjian-Ding I, Molitor E, Brossart P, von Lilienfeld-Toal M (2015): Comparison of antibiotic prophylaxis with cotrimoxazole/colistin (COT/COL) versus ciprofloxacin (CIP) in patients with acute myeloid leukemia.
Support Care Cancer 23: 1321-1329.
Online-Abstract

Nguyen MT, Kraft B, Yu W, Demircioglu DD, Hertlein T, Burian M, Schmaler M, Boller K, Bekeredjian-Ding I, Ohlsen K, Schittek B, Götz F (2015): The νSaα Specific Lipoprotein Like Cluster (lpl) of S. aureus USA300 Contributes to Immune Stimulation and Invasion in Human Cells.
PLOS Pathog 11: e1004984.
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Schmithausen RM, Kellner SR, Schulze-Geisthoevel SV, Hack S, Engelhart S, Bodenstein I, Al-Sabti N, Reif M, Fimmers R, Körber-Irrgang B, Harlizius J, Hoerauf A, Exner M, Bierbaum G, Petersen B, Bekeredjian-Ding I (2015): Eradication of methicillin-resistant Staphylococcus aureus and Enterobacteriaceae expressing extended-spectrum beta-lactamases on a model pig farm.
Appl Environ Microbiol 81: 7633-7643.
Online-Abstract

Schmithausen RM, Schulze-Geisthoevel SV, Stemmer F, El-Jade M, Reif M, Hack S, Meilaender A, Montabauer G, Fimmers R, Parcina M, Hoerauf A, Exner M, Petersen B, Bierbaum G, Bekeredjian-Ding I (2015): Analysis of Transmission of MRSA and ESBL-E among Pigs and Farm Personnel.
PLOS ONE 10: e0138173.
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Schurig U, Karo JO, Sicker U, Spindler-Raffel E, Häckel L, Spreitzer I, Bekeredjian-Ding I (2015): Aktuelles Konzept zur mikrobiologischen Sicherheit von zellbasierten Arzneimitteln.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 58: 1225-1232.
Online-Abstract