Paul-Ehrlich-Institut

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Infographic – Viral Hepatitis – from A to E

Text version

Viral Hepatitis – from A to E

Hepatitis is an inflammation of the liver. Infections with the hepatitis viruses A to E are often the cause of hepatitis. The viral infection can be chronic.

  • 28.7. world hepatitis day: Birthday of Dr. Blumberg, discoverer of the hepatitis B virus
    • 354 million people worldwide are living with hepatitis B or C.*
    • 20 million hepatitis E infections occur annually worldwide.*
    • 1,1 million people worldwide die of hepatitis B or C every year.*
    • 9,4 million people worldwide are treated for chronic hepatitis C virus infection.*

*source: WHO

Hepatitis A:

  • Effective vaccines are available
  • Never chronic, usually heals without serious complications
  • Specific treatment is not possible

Hepatitis B:

  • Effective vaccines are available
  • Can be severe and chronic, especially in young children and babies
  • Medicines cannot cure, but can reduce the viral load

Hepatitis C:

  • There is no vaccine
  • Usually asymptomatic, but often becomes chronic
  • Medicines are available

Hepatitis D:

  • Vaccination against hepatitis B also protects against hepatitis D
  • Requires the hepatitis B virus to multiply – in this combination leads to the most severe forms of progression
  • A medicine has been authorised since 2020

Hepatitis E:

  • There is no vaccine authorised in the EU
  • Usually cures without consequences, but severe and lethal courses are possible, especially for pregnant women
  • No specific therapy possible
  • Find out more about the vaccines authorised in Germany:
    www.pei.de/vaccines

Spread of Hepatitis Viruses:

A: Lack of food hygiene, polluted water, lack of sanitary facilities
B, C, D: Blood, sperm and other body fluids
E: In Germany mostly zoonotic, worldwide through contaminated drinking water, blood

Blood Donations

Blood donations are tested in Germany for the hepatitis viruses B and C, and since 2020 for E, in order to prevent transmission via blood products.