Paul-Ehrlich-Institut

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Re­search and Third-Par­ty Fund­ing

Funded research projects and third-party funded projects at the Paul-Ehrlich-Institut (PEI)

BMG | Federal Ministry of Health

Project ManagerProject DescriptionDuration
Dr Gabriele UngerActivity as WHO Collaborating Center for Blood Products an IVD Devices01.01.2010 - 31.12.2025
Prof Dr van Ger ZandbergenEstablishment of an assessment system for innovative adjuvants01.07.2015 - 31.03.2020
Dr Renate KönigRegulatory use of BigData strategies based on OMICS data for efficient development, approval and safe use of biological medicinal products01.12.2021 - 31.12.2026
Dr Renate KönigRegulatory use of AI-supported methods for the efficient evaluation and regulation of biomedical drugs01.03.2022 - 31.12.2024
Dr Renate KönigIntegrated Network for Monitoring and Identification of Infectious Disease Risks01.03.2022 - 31.12.2024
Prof Dr Ger van ZandbergenRegulatory research on quality data (physicochemical and functional assays) versus clinical data (PK and phase 3 efficacy study) in the approval of biosimilars01.10.2022 - 30.06.2025
Dr Heidi MeyerGHPP | Regulatory capacity building in the area of vaccines - Training and scientific advice for the establishment of the State Batch Tests (VaccRelease)01.01.2023 -31.12.2025
Dr Heidi MeyerGHPP | Regulatory capacity building in the area of vaccines - Training and advice on clinical trials and pharmacovigilance (VaccTrain 2.0)01.01.2023 - 31.12.2025
Dr Jens ReinhardtGHPP | Availability, quality and safety of blood and blood products in Africa (BloodTrain Next Generation)01.01.2023 - 31.12.2025
Prof Dr Zoe WaiblerDevelopment of methods for comparative analysis of the potency of monoclonal antibodies01.04.2023 - 31.03.2026
PD Dr Christel KampRaman spectroscopy as a digital, non-destructive method of quality control in batch testing to improve the quality of supply01.05.2023 - 30.04.2026

BMBF | Federal Ministry of Education and Research

Project ManagerProject DescriptionDuration
Dr Nadine Kirsch-Stefan,
Dr Christoph Conrad
OSRA-PEI01.01.2021 - 28.02.2026
Dr Michael MühlebachJoint project | Emergency Vaccines PEI-TP: Recombinant measles virus vaccine platform01.01.2021 - 28.02.2026
Dr Bevan SawatskyDZIF | German Center for Infection Research: Animal facility for testing vaccines and antivirals against newly emerging infections under BSL 3/4 conditions01.02.2021 - 28.02.2026
Dr Martina Schüßler-LenzRegulatorische Analyse und Optimierung der Translation von Entwicklungskandidaten im DKTK01.06.2021 - 31.05.2024
Prof Dr Oleg Krut,
Dr Ingo Spreitzer
Establishment of the monocyte activation test in the risk assessment of masked endotoxins in medicinal products (PyroSafe)01.04.2022 - 31.03.2025
Dr Olga TicháAlternative methods | Functional assay for B cell activation by toxoid vaccines (BCELL-ACT-2)01.08.2022 - 31.07.2024
Prof Dr Zoltan IvicsNoviCARAZA - AML treatment with non-viral CAR-NK cells plus AZA01.01.2023 - 31.12.2025
Dr Elisabeth BalksAlternative methods: development of an antibody-based, functional and a spectroscopic in vitro alternative for batch testing of bovine tuberculin (tuberculin)01.04.2023 - 31.03.2026
Dr Sarah Altrichter-DünnesPDU_CARB-X: Product Development Unit (PDU) of the German Centre for Infection Research (DZIF) as CARB-X Accelerator01.10.2023 - 31.12.2026

DFG | German Research Foundation

Project ManagerProject DescriptionDuration
Prof Dr Ralf R. Tönjes
Dr Antonia W. Godehardt
Biology of xenogenic cell, tissue and organ transplantation from basic research to clinical application01.07.2012 - 30.06.2024
Dr Bevan Sawatsky
Dr Christian Pfaller
Mechanistic studies of morbillivirus-associated immunosuppression and antiviral immune responses against these viruses01.01.2021 - 31.12.2021
Dr Michael MühlebachBroad-spectrum HPV vaccine based on recombinant measles01.10.2021 - 30.09.2024
Dr Renate KönigTargeting converging mechanisms of inefficient immunity in tumor diseases and chronic infections01.01.2022 - 31.12.2025
Prof Dr Eberhard HildtHBV over time: characteristics of viral pathogenesis in different disease phases01.03.2022 - 28.02.2025
Dr Jessica RoosInvestigation of nitroalkylation as a novel endogenous regulatory mechanism and therapeutic target on the ubiquitin-proteasome system01.01.2023 - 31.12.2025
Prof Dr Thorsten Jürgen MaierInvestigation on the effects of carbapenems on leukocyte-endothelial interaction in models of pulmonary inflammation and viral infection01.02.2023 - 31.01.2026
Dr Jacomina Krijnse-LockerDeciphering the molecular mechanism of vaccinia virus mRNA release01.04.2023 - 31.03.2026
Prof Dr Zoltan IvicsTargeted genome integration through genetically engineered transposon and CRISPR/Cas9 components01.09.2023 - 31.08.2026

EU | European Union

Project ManagerProject DescriptionDuration
Prof Dr Zoe WaiblerimSAVAR | Emerging translational safety technologies and tools for interrogating human immuno-biology01.11.2019 - 31.10.2025
Prof Dr Isabelle Bekeredjian-DingCOMBINE | Collaboration for Prevention and Treatment of MDR Bacterial Infections01.11.2019 - 31.10.2025
Prof Dr Isabelle Bekeredjian-DingTIPAT | Training towards Personalized Antibiotic Treatment01.03.2020 - 29.02.2024
Prof Dr Zoltan Ivics
Prof Dr Christian Buchholz
T2EVOLVE | Accelerating Development and Improving Access to CAR and TCR-engineered T cell therapy01.01.2021 - 31.12.2025
Dr J. HartmannT-OP | Training Network for Optimizing Adoptive T cell Therapy of Cancer01.03.2021 - 28.02.2025
Prof Dr Isabelle Bekeredjian-DingINNO4VAC | Innovations to accelerate vaccine development and manufacture01.09.2021 - 28.02.2027
Dr Thomas HolzhauserALLPreT | Allergenicity Prediction Toolbox for novel foods01.09.2022 - 28.02.2025
Prof Dr Isabelle Bekeredjian-Ding
Dr Maximilian Ehrhardt
CHESSMEN | Coordination and Harmonization of the Existing Systems against Shortage of Medicine – European Network16.01.2023 - 15.01.2025
Bettina ZiegeleIncreaseNET | Supporting the increased capacity and competence building of the EU medicines regulatory network01.01.2024 - 31.12.2026

LOEWE-Centres | State of Hesse

Project ManagerProject DescriptionDuration
Prof Dr Eberhard Hildt, Dr Daniela BenderNovel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Targets for antiviral strategies against the Zika virus01.01.2022 - 31.12.2024
Prof Dr Eberhard HildtNovel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Identification of cellular targets for antiviral strategies - Inhibition of virus release through modulation of cholesterol levels01.01.2022 - 31.12.2024
Prof Dr Ger van ZandbergenNovel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Characterisation of apoptotic parasites to identify new targets for the treatment of leishmaniasis01.01.2022 - 31.12.2024
Dr Jacomina Krijnse-LockerNovel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: W2 Professorship for Pathogen Imaging and Immunology01.01.2022 - 31.12.2024
Prof Dr Christian BuchholzVektor-Core01.01.2023 - 31.12.2025
Dr Frederic ThalheimerGeneration of CAR-T cells targeting circulating tumor cells emerged from solid tumors01.01.2024 - 31.12.2024
Prof Dr Ger van ZandbergenNovel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: A CRISPR screen in L. major to identify the MOA and drug resistance mechanism of 1o and 1c15.12.2023 - 31.12.2024

Various

DAAD| German Academic Exchange Service

Project ManagerProject DescriptionDuration
Dr Stephan ScheurerAnti-allergic effect of apple derived pectin: A novel immunomodulatory function01.01.2024-31.12.2025

EDQM | European Directorate for the Quality of Medicine

Project ManagerProject DescriptionDuration
Prof Dr Stefan ViethsRecombinant major allergens (BRPs and assay methods)undetermined

German Cancer Aid

Project ManagerProject DescriptionDuration
Prof Dr Christian BuchholzIn vivo generation of CAR T cells in an immunocompetent large animal model01.06.2021 - 31.05.2024

German José Carreras Foundation

Project ManagerProject DescriptionDuration
Dr Jessica HartmannThe importance of the bone marrow microvasculature for the therapeutic effectiveness of CAR NK cells and CAR T cells in acute leukemia15.11.2021 - 14.11.2024

ISBT | International Society of Blood Transfusion

Project ManagerProject DescriptionDuration
Dr Marcel PraxEstablishment of platelet bacterial reference strains in BioBall formatfrom 2019

Medical Research Council

Project ManagerProject DescriptionDuration
Prof Dr Zoltan IvicsDevelopment of a transcriptional signature-based tumorigenesis (TraST) classifier to evaluate the genotoxic risk of genetically engineered human T-cells15.01.24 - 14.01.27

Rudolf Marx Foundation

Project ManagerProject DescriptionDuration
Prof Dr Ger van Zandbergen
Prof Dr Jacomine Krijnse Locker
Studies on the influence of a2-macroglobulin on the infectivity of SARS-CoV-2 in cell cultureindefinite

SET | Foundation for the Promotion of Research into Alternative and Complementary Methods to Limit Animal Experiments

Project ManagerProject DescriptionDuration
PD Dr Christel KampSpectroscopic determination of vaccine components01.01.2023 - 31.12.2024

Phospholipid Research Center

Project ManagerProject DescriptionDuration
Prof Dr Christian BuchholzReceptor-targeted lipid nanoparticles for mRNA delivery into T lymphocytes01.03.24 - 28.02.26

Updated: 18.03.2024