Research and Third-Party Funding
Funded research projects and third-party funded projects at the Paul-Ehrlich-Institut (PEI)
BMG | Federal Ministry of Health
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Gabriele Unger | Activity as WHO Collaborating Center for Blood Products an IVD Devices | 01.01.2010 - 31.12.2025 |
| Dr Christoph Conrad | GHPP | Global Health Protection Programme RegTrain-VaccTrain: Regulatory training and advice in the field of vaccines and biomedical therapeutics | 01.01.2019 - 31.12.2021 |
| Dr Anneliese Hilger | GHPP | Global Health Protection Programme BloodTrain: Availability, safety and quality of blood and blood products | 01.01.2019 - 31.12.2021 |
| Prof Dr Veronika von Messling | Safety of vaccines against zika and other flaviviruses | 01.12.2016 - 31.12.2023 |
| Prof Dr Gerald G. Schumann | Safety of human pluripotent stem cells in the use for somatic cell therapy | 01.01.2019 - 31.12.2021 |
| Prof Dr van Ger Zandbergen | Establishment of an assessment system for innovative adjuvants | 01.07.2015 - 31.03.2020 |
| Prof Dr Christian Buchholz | Studies on acute side effects of CAR-T cells in mouse models | 01.11.2018 - 31.10.2022 |
| Dr Michael Mühlebach | Safety and standardisation of measles vaccine strain derived vaccines against highly pathogenic bacteria | 01.11.2018 - 28.02.2022 |
BMBF | Federal Ministry of Education and Research
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr von Veronika Messling | PEG-alternative polymers for bio-conjugation to proteins (Next-PEG) - subproject: safety and efficacy study of different interferon (IFN) alpha-2a conjugates | 01.08.2018 - 31.07.2021 |
| Dr Christoph Conrad | DZIF | German Center for Infection Research: PDU CARB-X Accelerator: project management, consulting and regulatory aspects of antibiotic development | 01.01.2019 - 31.12.2021 |
| Prof Dr Stefan Vieths | DIFAMEM | Dietary intervention in food allergy: microbiome, epigenetic and metabolomic interactions | 01.03.2019 - 28.02.2022 |
| Prof Dr Isabelle Bekeredjian-Ding | Alternative methods to animal testing: B-CELL-ACT - functional test for B-cell activation by toxoid vaccines | 01.04.2019 - 31.03.2022 |
| Dr. Verena Klümpers, Dr. Micha Nübling, Dr. Alexander Pinz | BISKIT | Blood Information System for Crisis Intervention and Management - Subproject: Processes and Structures | 01.04.2020 - 31.03.2023 |
| Dr Michael Mühlebach | MeV-derived Vaccine candidates protecting against COVID-19 | 15.04.2020 - 14.04.2021 |
| Dr Nadine Kirsch-Stefan, Dr Christoph Conrad | OSRA-PEI | 01.01.2021 - 28.02.2026 |
| Dr Michael Mühlebach | Joint project | Emergency Vaccines PEI-TP: Recombinant measles virus vaccine platform | 01.01.2021 - 28.02.2026 |
| Dr Bevan Sawatsky | DZIF | German Center for Infection Research: Animal facility for testing vaccines and antivirals against newly emerging infections under BSL 3/4 conditions | 01.02.2021 - 28.02.2026 |
| Prof Dr Christian Buchholz | COMMUTE | (16GW0339) Drug delivery: combinatorial and multidisciplinary targeting of effective gene therapy vectors - rational design of receptor targeting AAV particles with DARPins | 01.03.2021 - 29.02.2024 |
DFG | German Research Foundation
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Renate König | Influence on inflammation and DNA damage response and their effect on HIV-1 infection and tumor diseases | 01.01.2018 - 31.12.2021 |
| Dr Stephan Scheurer | Immune modulating mechanisms of flagellin A (FlaA)-fusion proteins at the interface between cell metabolism, TLR signaling, and inflammasome activation: WP2: TLR5/NLRC4-mediated activation | 01.03.2019 - 28.02.2022 |
| Dr Stefan Schülke | Immune modulating mechanisms of flagellin A (FlaA)-fusion proteins at the interface between cell metabolism, TLR signaling, and inflammasome activation: WP1: Immune metabolism | 01.05.2019 - 30.04.2022 |
| Dr Thorsten Jürgen Maier | Investigation of novel cysteine-reactive nitrofatty acids with covalent attack on inflammation-relevant drug targets | 01.11.2019 - 31.10.2022 |
| Prof Dr Ralf R. Tönjes Dr Antonia W. Godehardt | Biology of xenogenic cell, tissue and organ transplantation from basic research to clinical application | 01.07.2012 - 30.06.2024 |
| Prof Dr Zoltán Ivics | Modeling of cerebellar pathology in ataxia-telangiectasia: study of ATM-deficient mice versus human iPS cells | 01.01.2020 - 31.12.2022 |
| Prof Dr Ute Modlich | Hematopoietic stem cell-directed gene therapy for the treatment of ataxia telangiectasia (A-T) | 01.04.2020 - 31.03.2023 |
| Prof Dr Ute Modlich | Epcr expression and Epcr / Par1 signaling pathways in Mpl deficient and normal hematopoiesis during transplantation | 01.06.2020 - 31.05.2023 |
| Prof Dr Ger van Zandbergen | Cell death dependence of the emergence of leishmania from infected host macrophages | 01.12.2020 - 30.11.2023 |
| Dr Bevan Sawatsky Dr Christian Pfaller | Intra- and inter-host dynamics and genetic plasticity of morbilliviruses | 01.01.2021 - 30.06.2021 |
| Dr Renate König | Investigation of the cellular mechanisms of the PQBP1-mediated innate immune response to HIV-1 | 01.10.2020 - 30.09.2023 |
EU | European Union
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Elisabeth Balks Dr Andreas Reuter Prof Dr Isabelle Bekeredjian-Ding | VAC2VAC | Vaccine batch to vaccine batch comparison by consistency testing | 01.03.2016 - 28.02.2022 |
| Prof Dr von Veronika Messling | Crimean-Congo haemorrhagic fever vaccine (CCHFVaccine) | 01.01.2017 - 31.12.2022 |
| Prof Dr Zoltan Ivics | CARAMBA | SLAMF7-CAR T cells prepared by sleeping beauty gene-transfer for immunotherapy of multiple myeloma - a rare hematologic disease | 01.01.2018 - 30.04.2022 |
| Priv-Doz Dr Dorothea Stahl Birgit Haschberger | GAPP | Facilitating the authorisation of preparation process for blood and tissues and cells | 01.05.2018 - 30.04.2021 |
| Bettina Ziegele | STARS | Strengthening training of academia in regulatory sciences and supporting regulatory scientific advice | 01.01.2019 - 30.06.2022 |
| Prof Dr Christian Buchholz | STACCATO | Enhancing the manufacture of advanced biological medicine through high-resolution analysis of single cells | 01.01.2019 - 31.12.2022 |
| PD Dr. Benjamin Hofner | EU-PEARL | Integrated research platforms enabling patient-centric drug development | 01.11.2019 - 30.04.2023 |
| Prof Dr Zoe Waibler | imSAVAR | Emerging translational safety technologies and tools for interrogating human immuno-biology | 01.11.2019 - 31.10.2025 |
| Prof Dr Isabelle Bekeredjian-Ding | COMBINE | Collaboration for Prevention and Treatment of MDR Bacterial Infections | 01.11.2019 - 31.10.2025 |
| Prof Dr Isabelle Bekeredjian-Ding | TIPAT | Training towards Personalized Antibiotic Treatment | 01.03.2020 - 29.02.2024 |
| Prof Dr Zoltan Ivics Prof Dr Christian Buchholz | T2EVOLVE | Accelerating Development and Improving Access to CAR and TCR-engineered T cell therapy | 01.01.2021 - 31.12.2025 |
| Dr J. Hartmann | T-OP | Training Network for Optimizing Adoptive T cell Therapy of Cancer | 01.03.2021 - 28.02.2025 |
LOEWE-Centres | State of Hesse
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Eberhard Hildt | LOEWE Center DRUID | Novel drug targets against poverty-related and neglected tropical infectious diseases: identification of target structures for the therapy of hepatitis E and C | 01.01.2018 - 31.12.2021 |
| Prof Dr Eberhard Hildt Dr Daniela Ploen Dr Sally Baylis | LOEWE Center DRUID | Novel drug targets against poverty-related and neglected tropical infectious diseases: characterisation of the ZIKV/host interaction | 01.01.2018 - 31.12.2021 |
| Prof Dr van Ger Zandbergen | LOEWE Center DRUID | Novel drug targets against poverty-related and neglected tropical infectious diseases: W2 professorship for pathogen imaging and immunology | 01.01.2018 - 31.12.2021 |
| Prof Dr van Ger Zandbergen | LOEWE Center DRUID | Novel drug targets against poverty-related and neglected tropical infectious diseases: characterisation of apoptotic parasites to identify new target molecules for the treatment of leishmaniasis | 01.01.2018 - 31.12.2021 |
| Prof Dr Barbara Schnierle | LOEWE Center DRUID | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Implementation of a chikungunya virus vaccine candidate based on self-amplifying RNA | 01.10.2020 - 30.09.2021 |
| Prof Dr Jacomina Krijnse Locker | LOEWE Center DRUID | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Correlated light- and electron microscopy reveals virus entry and disassembly | 01.01.2020 - 31.12.2021 |
| Prof Dr Ger van Zandbergen | LOEWE Center DRUID | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Parallel in vitro and in silico screening of small-molecule libraries against the key Leishmania enzyme glucose-6-phosphate dehydrogenase to identify first lead candidates | 01.07.2020 - 31.12.2021 |
| Prof Dr Eberhard Hildt | LOEWE Center DRUID | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: cholesterol modulators efficiently block HEV replication | 01.07.2020 - 31.12.2021 |
Various
BLE | Federal Office for Agriculture and Food
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Stefan Vieths Dr Melanie Albrecht | ZeBaP | Development and validation of a cell-based test system for the detection of traces of allergens and for the determination of the allergenic potential of processed foods | 01.04.2020 - 31.03.2023 |
| Dr Thomas Holzhauser | Development of an allergen-containing test biscuit for a special diet for babies - the food kiss (Solids-by-Kiss) | 01.01.2021 - 31.12.2023 |
CEPI | Coalition for Epidemic Preparedness Innovations
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Michael Mühlebach | Comparison of measles vectors in a murine model | 14.12.2018 - 30.06.2021 |
CEU | University San Pablo - CEU Madrid
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Stephan Scheurer | Scholarship Elisa Zubeldia: Gut microbiota and allergic enteritis | 18.01.2021 - 17.04.2021 |
CSC | China Scholarship Council
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Eberhard Hildt | Grant Qingyan Wu: Comaptative analysis of entry and release parameters for HBV | 09.10.2017 - 08.10.2021 |
| Prof Dr Eberhard Hildt | Grant Xingjian Wen: Crosstalk between HCV and GBP1 | 09.02.2018 - 09.02.2020 |
DAAD | German Academic Exchange Service
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Eberhard Hildt | Grant Sara Mohamed: Turnover of nonstructural proteins in HCV life cycle | 01.12.2017 - 30.09.2021 |
DGUV | German Statutory Accident Insurance
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof. Dr. Vera Mahler | Quality assurance of the diagnosis of occupational type I allergies | 01.11.2020 - 31.10.2023 |
EDQM | European Directorate for the Quality of Medicine
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Stefan Vieths | Recombinant major allergens (BRPs and assay methods) | undetermined |
FEI | Research Association of the German Food Industry
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Stefan Vieths Dr Stephan Scheurer | Examination of the health-promoting effect of pectins in food allergies | 01.04.2019 - 30.09.2021 |
German Cancer Aid
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Christian Buchholz | In vivo generation of CAR T cells in an immunocompetent large animal model | 01.06.2021 - 31.05.2024 |
Health Holland
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Christian Buchholz | Lentiviral biological pacemakers | 01.03.2020 - 28.02.2022 |
Innovation Committee of the Joint Federal Committee
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Brigitte Keller-Stanislawski | Feasibility study on the suitability of different data sources as a basis for improving pharmacovigilance of innovative therapies using multiple sclerosis as an example | 01.06.2019 - 31.05.2022 |
ISBT | International Society of Blood Transfusion
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Marcel Prax | Establishment of platelet bacterial reference strains in BioBall format | from 2019 |
NIH | National Institut of Health
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Christian Buchholz | Disabling the replication-competent HIV provirus in the reservoir by combined CRISPR-Cas action | 05.04.2019 - 05.04.2023 |
Rudolf Marx Foundation
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Ger van Zandbergen Prof Dr Jacomine Krijnse Locker | Studies on the influence of a2-macroglobulin on the infectivity of SARS-CoV-2 in cell culture | indefinite |
Updated: 31.03.2021
