Research and Third-Party Funding
Funded research projects and third-party funded projects at the Paul-Ehrlich-Institut (PEI)
BMG | Federal Ministry of Health
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Gabriele Unger | Activity as WHO Collaborating Center for Blood Products an IVD Devices | 01.01.2010 - 31.12.2025 |
| Dr Christoph Conrad | GHPP | Global Health Protection Programme RegTrain-VaccTrain: Regulatory training and advice in the field of vaccines and biomedical therapeutics | 01.01.2019 - 31.12.2022 |
| Dr Anneliese Hilger | GHPP | Global Health Protection Programme BloodTrain: Availability, safety and quality of blood and blood products | 01.01.2019 - 31.12.2022 |
| Prof Dr Veronika von Messling | Safety of vaccines against zika and other flaviviruses | 01.12.2016 - 31.12.2023 |
| Prof Dr Gerald G. Schumann | Safety of human pluripotent stem cells in the use for somatic cell therapy | 01.01.2019 - 31.12.2021 |
| Prof Dr van Ger Zandbergen | Establishment of an assessment system for innovative adjuvants | 01.07.2015 - 31.03.2020 |
| Prof Dr Christian Buchholz | Studies on acute side effects of CAR-T cells in mouse models | 01.11.2018 - 31.10.2022 |
| Dr Michael Mühlebach | Safety and standardisation of measles vaccine strain derived vaccines against highly pathogenic bacteria | 01.11.2018 - 28.02.2022 |
| Prof Dr Rainer Seitz Dr Christoph Conrad | GHPP | Global Health Protection Programme BloodTrain: Safety and quality of blood and blood products - support for the development of a regulatory structure and its adaptation to crisis situations in the partner countries | 01.04.2016 - 31.12.2022 |
| Dr Renate König | Regulatory use of BigData strategies based on OMICS data for efficient development, approval and safe use of biological medicinal products | 01.12.2021 - 31.12.2026 |
| Dr Renate König | Regulatory use of AI-supported methods for the efficient evaluation and regulation of biomedical drugs | 01.03.2022 - 31.12.2024 |
| Dr Renate König | Integrated Network for Monitoring and Identification of Infectious Disease Risks | 01.03.2022 - 31.12.2024 |
BMBF | Federal Ministry of Education and Research
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Stefan Vieths | DIFAMEM | Dietary intervention in food allergy: microbiome, epigenetic and metabolomic interactions | 01.03.2019 - 30.06.2023 |
| Dr. Verena Klümpers, Dr. Micha Nübling, Dr. Alexander Pinz | BISKIT | Blood Information System for Crisis Intervention and Management - Subproject: Processes and Structures | 01.04.2020 - 31.03.2023 |
| Dr Nadine Kirsch-Stefan, Dr Christoph Conrad | OSRA-PEI | 01.01.2021 - 28.02.2026 |
| Dr Michael Mühlebach | Joint project | Emergency Vaccines PEI-TP: Recombinant measles virus vaccine platform | 01.01.2021 - 28.02.2026 |
| Dr Bevan Sawatsky | DZIF | German Center for Infection Research: Animal facility for testing vaccines and antivirals against newly emerging infections under BSL 3/4 conditions | 01.02.2021 - 28.02.2026 |
| Prof Dr Christian Buchholz | COMMUTE | (16GW0339) Drug delivery: combinatorial and multidisciplinary targeting of effective gene therapy vectors - rational design of receptor targeting AAV particles with DARPins | 01.03.2021 - 29.02.2024 |
| Dr Martina Schüßler-Lenz | Regulatorische Analyse und Optimierung der Translation von Entwicklungskandidaten im DKTK | 01.06.2021 - 31.05.2024 |
| Prof Dr Oleg Krut, Dr Ingo Spreitzer | Establishment of the monocyte activation test in the risk assessment of masked endotoxins in medicinal products (PyroSafe) | 01.04.2022 - 31.03.2025 |
| Dr Richard Brown | VIRASCREEN - Production of cDNA libraries for the identification of new host factors involved in the replication of zoonotic viruses | 01.07.2022 - 31.12.2023 |
| Dr Olga Tichá | Alternative methods | Functional assay for B cell activation by toxoid vaccines (BCELL-ACT-2) | 01.08.2022 - 31.07.2024 |
DFG | German Research Foundation
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Stephan Scheurer | Immune modulating mechanisms of flagellin A (FlaA)-fusion proteins at the interface between cell metabolism, TLR signaling, and inflammasome activation: WP2: TLR5/NLRC4-mediated activation | 01.03.2019 - 31.12.2022 |
| Dr Stefan Schülke | Immune modulating mechanisms of flagellin A (FlaA)-fusion proteins at the interface between cell metabolism, TLR signaling, and inflammasome activation: WP1: Immune metabolism | 01.05.2019 - 31.12.2022 |
| Dr Thorsten Jürgen Maier | Investigation of novel cysteine-reactive nitrofatty acids with covalent attack on inflammation-relevant drug targets | 01.11.2019 - 31.10.2022 |
| Prof Dr Ralf R. Tönjes Dr Antonia W. Godehardt | Biology of xenogenic cell, tissue and organ transplantation from basic research to clinical application | 01.07.2012 - 30.06.2024 |
| Prof Dr Zoltán Ivics | Modeling of cerebellar pathology in ataxia-telangiectasia: study of ATM-deficient mice versus human iPS cells | 01.01.2020 - 31.12.2022 |
| Prof Dr Ute Modlich | Hematopoietic stem cell-directed gene therapy for the treatment of ataxia telangiectasia (A-T) | 01.04.2020 - 31.03.2023 |
| Prof Dr Ute Modlich | Epcr expression and Epcr / Par1 signaling pathways in Mpl deficient and normal hematopoiesis during transplantation | 01.06.2020 - 31.05.2023 |
| Prof Dr Ger van Zandbergen | Cell death dependence of the emergence of leishmania from infected host macrophages | 01.12.2020 - 30.11.2023 |
| Dr Bevan Sawatsky Dr Christian Pfaller | Mechanistic studies of morbillivirus-associated immunosuppression and antiviral immune responses against these viruses | 01.01.2021 - 31.12.2021 |
| Dr Renate König | Investigation of the cellular mechanisms of the PQBP1-mediated innate immune response to HIV-1 | 01.10.2020 - 30.09.2023 |
| Dr Michael Mühlebach | Broad-spectrum HPV vaccine based on recombinant measles | 01.10.2021 - 30.09.2024 |
| Dr Renate König | Targeting converging mechanisms of inefficient immunity in tumor diseases and chronic infections | 01.01.2022 - 31.12.2025 |
| Prof Dr Eberhard Hildt | HBV over time: characteristics of viral pathogenesis in different disease phases | 01.03.2022 - 28.02.2025 |
EU | European Union
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Elisabeth Balks Dr Andreas Reuter Prof Dr Isabelle Bekeredjian-Ding | VAC2VAC | Vaccine batch to vaccine batch comparison by consistency testing | 01.03.2016 - 28.02.2022 |
| Prof Dr von Veronika Messling | Crimean-Congo haemorrhagic fever vaccine (CCHFVaccine) | 01.01.2017 - 31.12.2022 |
| Prof Dr Zoltan Ivics | CARAMBA | SLAMF7-CAR T cells prepared by sleeping beauty gene-transfer for immunotherapy of multiple myeloma - a rare hematologic disease | 01.01.2018 - 30.04.2022 |
| Priv-Doz Dr Dorothea Stahl Birgit Haschberger | GAPP | Facilitating the authorisation of preparation process for blood and tissues and cells | 01.05.2018 - 31.01.2022 |
| Bettina Ziegele | STARS | Strengthening training of academia in regulatory sciences and supporting regulatory scientific advice | 01.01.2019 - 30.06.2022 |
| Prof Dr Christian Buchholz | STACCATO | Enhancing the manufacture of advanced biological medicine through high-resolution analysis of single cells | 01.01.2019 - 31.12.2022 |
| PD Dr. Benjamin Hofner | EU-PEARL | Integrated research platforms enabling patient-centric drug development | 01.11.2019 - 30.04.2023 |
| Prof Dr Zoe Waibler | imSAVAR | Emerging translational safety technologies and tools for interrogating human immuno-biology | 01.11.2019 - 31.10.2025 |
| Prof Dr Isabelle Bekeredjian-Ding | COMBINE | Collaboration for Prevention and Treatment of MDR Bacterial Infections | 01.11.2019 - 31.10.2025 |
| Prof Dr Isabelle Bekeredjian-Ding | TIPAT | Training towards Personalized Antibiotic Treatment | 01.03.2020 - 29.02.2024 |
| Prof Dr Zoltan Ivics Prof Dr Christian Buchholz | T2EVOLVE | Accelerating Development and Improving Access to CAR and TCR-engineered T cell therapy | 01.01.2021 - 31.12.2025 |
| Dr J. Hartmann | T-OP | Training Network for Optimizing Adoptive T cell Therapy of Cancer | 01.03.2021 - 28.02.2025 |
| Prof Dr Isabelle Bekeredjian-Ding | INNO4VAC | Innovations to accelerate vaccine development and manufacture | 01.09.2021 - 28.02.2027 |
| Dr Thomas Holzhauser | ALLPreT | Allergenicity Prediction Toolbox for novel foods | 01.09.2022 - 28.02.2025 |
LOEWE-Centres | State of Hesse
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr. Frederic Thalheimer | In situ CAR T cell generation in primary patient material using receptor-targeted AAV vectors | 01.01.2022 - 31.12.2022 |
| Prof Dr Eberhard Hildt | LOEWE Center DRUID | PaaP: Protease Activatable Antiviral Prodrugs | 01.10.2021 - 30.09.2023 |
| Prof Dr Eberhard Hildt, Dr. Daniela Bender | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Targets for antiviral strategies against the Zika virus | 01.01.2022 - 31.12.2024 |
| Prof Dr Eberhard Hildt | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Identification of cellular targets for antiviral strategies - Inhibition of virus release through modulation of cholesterol levels | 01.01.2022 - 31.12.2024 |
| Prof Dr Ger van Zandbergen | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Characterisation of apoptotic parasites to identify new targets for the treatment of leishmaniasis | 01.01.2022 - 31.12.2024 |
| Dr Jacomina Krijnse-Locker | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: W2 Professorship for Pathogen Imaging and Immunology | 01.01.2022 - 31.12.2024 |
Various
BLE | Federal Office for Agriculture and Food
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Stefan Vieths Dr Melanie Albrecht | ZeBaP | Development and validation of a cell-based test system for the detection of traces of allergens and for the determination of the allergenic potential of processed foods | 01.04.2020 - 31.03.2023 |
| Dr Thomas Holzhauser | Development of an allergen-containing test biscuit for a special diet for babies - the food kiss (Solids-by-Kiss) | 01.01.2021 - 31.12.2023 |
DGUV | German Statutory Accident Insurance
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof. Dr. Vera Mahler | Quality assurance of the diagnosis of occupational type I allergies | 01.11.2020 - 31.10.2023 |
EDQM | European Directorate for the Quality of Medicine
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Stefan Vieths | Recombinant major allergens (BRPs and assay methods) | undetermined |
German Cancer Aid
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Christian Buchholz | In vivo generation of CAR T cells in an immunocompetent large animal model | 01.06.2021 - 31.05.2024 |
German José Carreras Foundation
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Jessica Hartmann | The importance of the bone marrow microvasculature for the therapeutic effectiveness of CAR NK cells and CAR T cells in acute leukemia | 15.11.2021 - 14.11.2024 |
ISBT | International Society of Blood Transfusion
| Project Manager | Project Description | Duration |
|---|---|---|
| Dr Marcel Prax | Establishment of platelet bacterial reference strains in BioBall format | from 2019 |
NIH | National Institut of Health
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Christian Buchholz | Disabling the replication-competent HIV provirus in the reservoir by combined CRISPR-Cas action | 05.04.2019 - 05.04.2023 |
Rudolf Marx Foundation
| Project Manager | Project Description | Duration |
|---|---|---|
| Prof Dr Ger van Zandbergen Prof Dr Jacomine Krijnse Locker | Studies on the influence of a2-macroglobulin on the infectivity of SARS-CoV-2 in cell culture | indefinite |
Updated: 08.08.2022
