Research and Third-Party Funding
Funded research projects and third-party funded projects at the Paul-Ehrlich-Institut (PEI)
BMG | Federal Ministry of Health
Project Manager | Project Description | Duration |
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Dr Gabriele Unger | Activity as WHO Collaborating Center for Blood Products an IVD Devices | 01.01.2010 - 31.12.2025 |
Prof Dr van Ger Zandbergen | Establishment of an assessment system for innovative adjuvants | 01.07.2015 - 31.03.2020 |
Dr Renate König | Regulatory use of BigData strategies based on OMICS data for efficient development, approval and safe use of biological medicinal products | 01.12.2021 - 31.12.2026 |
Dr Renate König | Regulatory use of AI-supported methods for the efficient evaluation and regulation of biomedical drugs | 01.03.2022 - 31.12.2024 |
Dr Renate König | Integrated Network for Monitoring and Identification of Infectious Disease Risks | 01.03.2022 - 31.12.2024 |
Prof Dr Ger van Zandbergen | Regulatory research on quality data (physicochemical and functional assays) versus clinical data (PK and phase 3 efficacy study) in the approval of biosimilars | 01.10.2022 - 30.06.2025 |
Dr Heidi Meyer | GHPP | Regulatory capacity building in the area of vaccines - Training and scientific advice for the establishment of the State Batch Tests (VaccRelease) | 01.01.2023 -31.12.2025 |
Dr Heidi Meyer | GHPP | Regulatory capacity building in the area of vaccines - Training and advice on clinical trials and pharmacovigilance (VaccTrain 2.0) | 01.01.2023 - 31.12.2025 |
Dr Jens Reinhardt | GHPP | Availability, quality and safety of blood and blood products in Africa (BloodTrain Next Generation) | 01.01.2023 - 31.12.2025 |
Prof Dr Zoe Waibler | Development of methods for comparative analysis of the potency of monoclonal antibodies | 01.04.2023 - 31.03.2026 |
PD Dr Christel Kamp | Raman spectroscopy as a digital, non-destructive method of quality control in batch testing to improve the quality of supply | 01.05.2023 - 30.04.2026 |
BMBF | Federal Ministry of Education and Research
Project Manager | Project Description | Duration |
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Dr Nadine Kirsch-Stefan,
Dr Christoph Conrad | OSRA-PEI | 01.01.2021 - 28.02.2026 |
Dr Michael Mühlebach | Joint project | Emergency Vaccines PEI-TP: Recombinant measles virus vaccine platform | 01.01.2021 - 28.02.2026 |
Dr Bevan Sawatsky | DZIF | German Center for Infection Research: Animal facility for testing vaccines and antivirals against newly emerging infections under BSL 3/4 conditions | 01.02.2021 - 28.02.2026 |
Prof Dr Oleg Krut,
Dr Ingo Spreitzer | Establishment of the monocyte activation test in the risk assessment of masked endotoxins in medicinal products (PyroSafe) | 01.04.2022 - 31.03.2025 |
Dr Olga Tichá | Alternative methods | Functional assay for B cell activation by toxoid vaccines (BCELL-ACT-2) | 01.08.2022 - 31.07.2024 |
Prof Dr Zoltan Ivics | NoviCARAZA - AML treatment with non-viral CAR-NK cells plus AZA | 01.01.2023 - 31.12.2025 |
Dr Elisabeth Balks | Alternative methods: Development of an antibody-based, functional and a spectroscopic in vitro alternative for batch testing of bovine tuberculin (tuberculin) | 01.04.2023 - 31.03.2026 |
Dr Sarah Altrichter-Dünnes | PDU_CARB-X: Product Development Unit (PDU) of the German Centre for Infection Research (DZIF) as CARB-X Accelerator | 01.10.2023 - 31.12.2026 |
Dr Olga Tichá | Alternative methods: Characterisation of immunodominant epitopes of tetanus toxoid vaccines (TT-TOP) | 01.04.2024 - 31.03.2027 |
Dr Michael Mühlebach | SERIMM – Serotonin and immunomodulation in ME/CFS – Development and analysis of a SARS-CoV-2-induced golden hamster animal model for ME/CFS | 01.10.2024 - 31.12.2026 |
DFG | German Research Foundation
Project Manager | Project Description | Duration |
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Dr Bevan Sawatsky
Dr Christian Pfaller | Mechanistic studies of morbillivirus-associated immunosuppression and antiviral immune responses against these viruses | 01.01.2021 - 31.12.2021 |
Dr Michael Mühlebach | Broad-spectrum HPV vaccine based on recombinant measles | 01.10.2021 - 30.09.2024 |
Dr Renate König | Targeting converging mechanisms of inefficient immunity in tumor diseases and chronic infections | 01.01.2022 - 31.12.2025 |
Prof Dr Eberhard Hildt | HBV over time: characteristics of viral pathogenesis in different disease phases | 01.03.2022 - 28.02.2025 |
Dr Jessica Roos | Investigation of nitroalkylation as a novel endogenous regulatory mechanism and therapeutic target on the ubiquitin-proteasome system | 01.01.2023 - 31.12.2025 |
Prof Dr Thorsten Jürgen Maier | Investigation on the effects of carbapenems on leukocyte-endothelial interaction in models of pulmonary inflammation and viral infection | 01.02.2023 - 31.01.2026 |
Dr Jacomina Krijnse-Locker | Deciphering the molecular mechanism of vaccinia virus mRNA release | 01.04.2023 - 31.03.2026 |
Prof Dr Zoltan Ivics | Targeted genome integration through genetically engineered transposon and CRISPR/Cas9 components | 01.09.2023 - 31.08.2026 |
Prof Dr Ger van Zandbergen | Molecular and cellular characterisation of the importance of cell death processes for host cell exit and cell-to-cell transfer of Leishmania | 15.04.2024 - 14.04.2027 |
EU | European Union
Project Manager | Project Description | Duration |
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Prof Dr Zoe Waibler | imSAVAR | Emerging translational safety technologies and tools for interrogating human immuno-biology | 01.11.2019 - 31.10.2025 |
Prof Dr Isabelle Bekeredjian-Ding | COMBINE | Collaboration for Prevention and Treatment of MDR Bacterial Infections | 01.11.2019 - 31.10.2025 |
Prof Dr Isabelle Bekeredjian-Ding | TIPAT | Training towards Personalized Antibiotic Treatment | 01.03.2020 - 29.02.2024 |
Prof Dr Zoltan Ivics
Prof Dr Christian Buchholz | T2EVOLVE | Accelerating Development and Improving Access to CAR and TCR-engineered T cell therapy | 01.01.2021 - 31.12.2025 |
Dr J. Hartmann | T-OP | Training Network for Optimizing Adoptive T cell Therapy of Cancer | 01.03.2021 - 28.02.2025 |
Prof Dr Isabelle Bekeredjian-Ding | INNO4VAC | Innovations to accelerate vaccine development and manufacture | 01.09.2021 - 28.02.2027 |
Dr Thomas Holzhauser | ALLPreT | Allergenicity Prediction Toolbox for novel foods | 01.09.2022 - 28.02.2025 |
Prof Dr Isabelle Bekeredjian-Ding
Dr Maximilian Ehrhardt | CHESSMEN | Coordination and Harmonization of the Existing Systems against Shortage of Medicine – European Network | 16.01.2023 - 15.01.2025 |
Bettina Ziegele | IncreaseNET | Supporting the increased capacity and competence building of the EU medicines regulatory network | 01.01.2024 - 31.12.2026 |
Prof Dr Karin Metzner | EURL-IVD.1 | Harmonization process of European Reference Laboratories for in vitro diagnosis | 01.02.2024 - 31.01.2025 |
Prof Dr Christian Buchholz | ERDERA | European Rare Diseases Research Alliance | 01.09.2024 - 31.08.2031 |
LOEWE-Centres | State of Hesse
Project Manager | Project Description | Duration |
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Prof Dr Eberhard Hildt, Dr Daniela Bender | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Targets for antiviral strategies against the Zika virus | 01.01.2022 - 31.12.2024 |
Prof Dr Eberhard Hildt | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Identification of cellular targets for antiviral strategies - Inhibition of virus release through modulation of cholesterol levels | 01.01.2022 - 31.12.2024 |
Prof Dr Ger van Zandbergen | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Characterisation of apoptotic parasites to identify new targets for the treatment of leishmaniasis | 01.01.2022 - 31.12.2024 |
Dr Jacomina Krijnse-Locker | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: W2 Professorship for Pathogen Imaging and Immunology | 01.01.2022 - 31.12.2024 |
Prof Dr Christian Buchholz | Vektor-Core | 01.01.2023 - 31.12.2025 |
Dr Frederic Thalheimer | Generation of CAR-T cells targeting circulating tumor cells emerged from solid tumors | 01.01.2024 - 31.12.2024 |
Prof Dr Ger van Zandbergen | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: A CRISPR screen in L. major to identify the MOA and drug resistance mechanism of 1o and 1c | 15.12.2023 - 31.12.2024 |
Prof Dr Christian Buchholz | LOEWE CARISMa | Optimisation of CAR cell therapies by influencing the immunosuppressive tumour microenvironment | 01.01.2025 - 31.12.2028 |
Various
DAAD | German Academic Exchange Service
Project Manager | Project Description | Duration |
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Dr Stephan Scheurer | Anti-allergic effect of apple derived pectin: A novel immunomodulatory function | 01.01.2024-31.12.2025 |
EDQM | European Directorate for the Quality of Medicine
Project Manager | Project Description | Duration |
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Prof Dr Stefan Vieths | Recombinant major allergens (BRPs and assay methods) | undetermined |
German José Carreras Foundation
Project Manager | Project Description | Duration |
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Dr Jessica Hartmann | The importance of the bone marrow microvasculature for the therapeutic effectiveness of CAR NK cells and CAR T cells in acute leukemia | 15.11.2021 - 14.11.2024 |
ISBT | International Society of Blood Transfusion
Project Manager | Project Description | Duration |
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Dr Marcel Prax | Establishment of platelet bacterial reference strains in BioBall format | from 2019 |
Medical Research Council
Project Manager | Project Description | Duration |
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Prof Dr Zoltan Ivics | Development of a transcriptional signature-based tumorigenesis (TraST) classifier to evaluate the genotoxic risk of genetically engineered human T-cells | 15.01.24 - 14.01.27 |
Rudolf Marx Foundation
Project Manager | Project Description | Duration |
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Prof Dr Ger van Zandbergen
Prof Dr Jacomine Krijnse Locker | Studies on the influence of a2-macroglobulin on the infectivity of SARS-CoV-2 in cell culture | indefinite |
SET | Foundation for the Promotion of Research into Alternative and Complementary Methods to Limit Animal Experiments
Project Manager | Project Description | Duration |
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PD Dr Christel Kamp | Spectroscopic determination of vaccine components | 01.01.2023 - 31.12.2024 |
Phospholipid Research Center
Project Manager | Project Description | Duration |
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Prof Dr Christian Buchholz | Receptor-targeted lipid nanoparticles for mRNA delivery into T lymphocytes | 01.03.24 - 28.02.26 |
FIMABIS | Fundacion Para La Investigacion De Malaga Enbiomedicina Y Salud
Project Manager | Project Description | Duration |
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Dr Stephan Scheurer | Analysis of the clinical efficacy and immunomodulatory effect of pectin in LTP allergic patients through a placebocontrolled intervention study and long-term follow-up | 01.01.2024 - 31.12.2026 |
SNF | Swiss National Foundation
Project Manager | Project Description | Duration |
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Dr Renate König | Molecular Mechanisms of Human Interferon System Deficiency | 01.01.2025 - 31.12.2026 |