Re­search and Third-Par­ty Fund­ing

Funded research projects and third-party funded projects at the Paul-Ehrlich-Institut (PEI)

BMG | Federal Ministry of Health

Project ManagerProject DescriptionDuration
Dr Gabriele UngerActivity as WHO Collaborating Center for Blood Products an IVD Devices01.01.2010 - 31.12.2025
Dr Christoph ConradGHPP | Global Health Protection Programme RegTrain-VaccTrain: Regulatory training and advice in the field of vaccines and biomedical therapeutics01.01.2019 - 31.12.2022
Dr Anneliese HilgerGHPP | Global Health Protection Programme BloodTrain: Availability, safety and quality of blood and blood products01.01.2019 - 31.12.2022
Prof Dr Veronika von MesslingSafety of vaccines against zika and other flaviviruses01.12.2016 - 31.12.2023
Prof Dr Gerald G. SchumannSafety of human pluripotent stem cells in the use for somatic cell therapy01.01.2019 - 31.12.2021
Prof Dr van Ger ZandbergenEstablishment of an assessment system for innovative adjuvants01.07.2015 - 31.03.2020
Prof Dr Christian BuchholzStudies on acute side effects of CAR-T cells in mouse models01.11.2018 - 31.10.2022
Dr Michael MühlebachSafety and standardisation of measles vaccine strain derived vaccines against highly pathogenic bacteria01.11.2018 - 28.02.2022
Prof Dr Rainer Seitz
Dr Christoph Conrad
GHPP | Global Health Protection Programme BloodTrain: Safety and quality of blood and blood products - support for the development of a regulatory structure and its adaptation to crisis situations in the partner countries01.04.2016 - 31.12.2022
Dr Renate KönigRegulatory use of BigData strategies based on OMICS data for efficient development, approval and safe use of biological medicinal products01.12.2021 - 31.12.2026

BMBF | Federal Ministry of Education and Research

Project ManagerProject DescriptionDuration
Prof Dr Stefan ViethsDIFAMEM | Dietary intervention in food allergy: microbiome, epigenetic and metabolomic interactions 01.03.2019 - 28.02.2022
Prof Dr Isabelle Bekeredjian-DingAlternative methods to animal testing: B-CELL-ACT - functional test for B-cell activation by toxoid vaccines01.04.2019 - 31.03.2022
Dr. Verena Klümpers,
Dr. Micha Nübling,
Dr. Alexander Pinz
BISKIT | Blood Information System for Crisis Intervention and Management - Subproject: Processes and Structures01.04.2020 - 31.03.2023
Dr Nadine Kirsch-Stefan,
Dr Christoph Conrad
OSRA-PEI01.01.2021 - 28.02.2026
Dr Michael MühlebachJoint project | Emergency Vaccines PEI-TP: Recombinant measles virus vaccine platform01.01.2021 - 28.02.2026
Dr Bevan SawatskyDZIF | German Center for Infection Research: Animal facility for testing vaccines and antivirals against newly emerging infections under BSL 3/4 conditions01.02.2021 - 28.02.2026
Prof Dr Christian BuchholzCOMMUTE | (16GW0339) Drug delivery: combinatorial and multidisciplinary targeting of effective gene therapy vectors - rational design of receptor targeting AAV particles with DARPins01.03.2021 - 29.02.2024
Dr Bevan SawatskyDZIF | German Center for Infection Research: Use of recombinant bacterial membrane vesicles (BMVs) in vaccination against MERSCoV and H1N1 influenza virus01.06.2021 - 28.02.2022
Dr Martina Schüßler-LenzRegulatorische Analyse und Optimierung der Translation von Entwicklungskandidaten im DKTK01.06.2021 - 31.05.2024

DFG | German Research Foundation

Project ManagerProject DescriptionDuration
Dr Stephan ScheurerImmune modulating mechanisms of flagellin A (FlaA)-fusion proteins at the interface between cell metabolism, TLR signaling, and inflammasome activation: WP2: TLR5/NLRC4-mediated activation01.03.2019 - 31.12.2022
Dr Stefan SchülkeImmune modulating mechanisms of flagellin A (FlaA)-fusion proteins at the interface between cell metabolism, TLR signaling, and inflammasome activation: WP1: Immune metabolism01.05.2019 - 31.12.2022
Dr Thorsten Jürgen MaierInvestigation of novel cysteine-reactive nitrofatty acids with covalent attack on inflammation-relevant drug targets01.11.2019 - 31.10.2022
Prof Dr Ralf R. Tönjes
Dr Antonia W. Godehardt
Biology of xenogenic cell, tissue and organ transplantation from basic research to clinical application01.07.2012 - 30.06.2024
Prof Dr Zoltán IvicsModeling of cerebellar pathology in ataxia-telangiectasia: study of ATM-deficient mice versus human iPS cells01.01.2020 - 31.12.2022
Prof Dr Ute ModlichHematopoietic stem cell-directed gene therapy for the treatment of ataxia telangiectasia (A-T)01.04.2020 - 31.03.2023
Prof Dr Ute ModlichEpcr expression and Epcr / Par1 signaling pathways in Mpl deficient and normal hematopoiesis during transplantation01.06.2020 - 31.05.2023
Prof Dr Ger van ZandbergenCell death dependence of the emergence of leishmania from infected host macrophages01.12.2020 - 30.11.2023
Dr Bevan Sawatsky
Dr Christian Pfaller
Mechanistic studies of morbillivirus-associated immunosuppression and antiviral immune responses against these viruses01.01.2021 - 31.12.2021
Dr Renate KönigInvestigation of the cellular mechanisms of the PQBP1-mediated innate immune response to HIV-101.10.2020 - 30.09.2023
Dr Michael MühlebachBroad-spectrum HPV vaccine based on recombinant measles01.10.2021 - 30.09.2024
Dr Renate KönigTargeting converging mechanisms of inefficient immunity in tumor diseases and chronic infections01.01.2022 - 31.12.2025

EU | European Union

Project ManagerProject DescriptionDuration
Dr Elisabeth Balks
Dr Andreas Reuter
Prof Dr Isabelle Bekeredjian-Ding
VAC2VAC | Vaccine batch to vaccine batch comparison by consistency testing01.03.2016 - 28.02.2022
Prof Dr von Veronika MesslingCrimean-Congo haemorrhagic fever vaccine (CCHFVaccine)01.01.2017 - 31.12.2022
Prof Dr Zoltan IvicsCARAMBA | SLAMF7-CAR T cells prepared by sleeping beauty gene-transfer for immunotherapy of multiple myeloma - a rare hematologic disease01.01.2018 - 30.04.2022
Priv-Doz Dr Dorothea Stahl
Birgit Haschberger
GAPP | Facilitating the authorisation of preparation process for blood and tissues and cells01.05.2018 - 31.01.2022
Bettina ZiegeleSTARS | Strengthening training of academia in regulatory sciences and supporting regulatory scientific advice01.01.2019 - 30.06.2022
Prof Dr Christian BuchholzSTACCATO | Enhancing the manufacture of advanced biological medicine through high-resolution analysis of single cells01.01.2019 - 31.12.2022
PD Dr. Benjamin HofnerEU-PEARL | Integrated research platforms enabling patient-centric drug development01.11.2019 - 30.04.2023
Prof Dr Zoe WaiblerimSAVAR | Emerging translational safety technologies and tools for interrogating human immuno-biology01.11.2019 - 31.10.2025
Prof Dr Isabelle Bekeredjian-DingCOMBINE | Collaboration for Prevention and Treatment of MDR Bacterial Infections01.11.2019 - 31.10.2025
Prof Dr Isabelle Bekeredjian-DingTIPAT | Training towards Personalized Antibiotic Treatment01.03.2020 - 29.02.2024
Prof Dr Zoltan Ivics
Prof Dr Christian Buchholz
T2EVOLVE | Accelerating Development and Improving Access to CAR and TCR-engineered T cell therapy01.01.2021 - 31.12.2025
Dr J. HartmannT-OP | Training Network for Optimizing Adoptive T cell Therapy of Cancer 01.03.2021 - 28.02.2025
Prof Dr Isabelle Bekeredjian-DingINNO4VAC | Innovations to accelerate vaccine development and manufacture01.09.2021 - 28.02.2027

LOEWE-Centres | State of Hesse

Project ManagerProject DescriptionDuration
Dr. Frederic ThalheimerIn situ CAR T cell generation in primary patient material using receptor-targeted AAV vectors01.01.2022 - 31.12.2022
Prof Dr Eberhard HildtLOEWE Center DRUID | PaaP: Protease Activatable Antiviral Prodrugs01.10.2021 - 30.09.2023


BLE | Federal Office for Agriculture and Food

Project ManagerProject DescriptionDuration
Prof Dr Stefan Vieths
Dr Melanie Albrecht
ZeBaP | Development and validation of a cell-based test system for the detection of traces of allergens and for the determination of the allergenic potential of processed foods01.04.2020 - 31.03.2023
Dr Thomas HolzhauserDevelopment of an allergen-containing test biscuit for a special diet for babies - the food kiss (Solids-by-Kiss)01.01.2021 - 31.12.2023

DGUV | German Statutory Accident Insurance

Project ManagerProject DescriptionDuration
Prof. Dr. Vera Mahler  Quality assurance of the diagnosis of occupational type I allergies01.11.2020 - 31.10.2023

EDQM | European Directorate for the Quality of Medicine

Project ManagerProject DescriptionDuration
Prof Dr Stefan ViethsRecombinant major allergens (BRPs and assay methods)undetermined

FEI | Research Association of the German Food Industry

Project ManagerProject DescriptionDuration
Prof Dr Stefan Vieths
Dr Stephan Scheurer
Examination of the health-promoting effect of pectins in food allergies01.04.2019 - 31.03.2022

German Cancer Aid

Project ManagerProject DescriptionDuration
Prof Dr Christian BuchholzIn vivo generation of CAR T cells in an immunocompetent large animal model01.06.2021 - 31.05.2024

German José Carreras Foundation

Project ManagerProject DescriptionDuration
Dr Jessica HartmannThe importance of the bone marrow microvasculature for the therapeutic effectiveness of CAR NK cells and CAR T cells in acute leukemia15.11.2021 - 14.11.2024

Health Holland

Project ManagerProject DescriptionDuration
Prof Dr Christian BuchholzLentiviral biological pacemakers01.03.2020 - 28.02.2022

Innovation Committee of the Joint Federal Committee

Project ManagerProject DescriptionDuration
Dr Brigitte Keller-StanislawskiFeasibility study on the suitability of different data sources as a basis for improving pharmacovigilance of innovative therapies using multiple sclerosis as an example01.06.2019 - 31.05.2022

ISBT | International Society of Blood Transfusion

Project ManagerProject DescriptionDuration
Dr Marcel PraxEstablishment of platelet bacterial reference strains in BioBall formatfrom 2019

NIH | National Institut of Health

Project ManagerProject DescriptionDuration
Prof Dr Christian BuchholzDisabling the replication-competent HIV provirus in the reservoir by combined CRISPR-Cas action05.04.2019 - 05.04.2023

Rudolf Marx Foundation

Project ManagerProject DescriptionDuration
Prof Dr Ger van Zandbergen
Prof Dr Jacomine Krijnse Locker
Studies on the influence of a2-macroglobulin on the infectivity of SARS-CoV-2 in cell cultureindefinite

Updated: 25.01.2022