Paul-Ehrlich-Institut

Re­search and Third-Par­ty Fund­ing

Funded research projects and third-party funded projects at the Paul-Ehrlich-Institut (PEI)

BMG | Federal Ministry of Health

Project ManagerProject DescriptionDuration
Dr Gabriele UngerActivity as WHO Collaborating Center for Blood Products an IVD Devices01.01.2010 - 31.12.2025
Dr Christoph ConradGHPP | Global Health Protection Programme RegTrain-VaccTrain: Regulatory training and advice in the field of vaccines and biomedical therapeutics01.01.2019 - 31.12.2021
Dr Anneliese HilgerGHPP | Global Health Protection Programme BloodTrain: Availability, safety and quality of blood and blood products01.01.2019 - 31.12.2021
Prof Dr Veronika von MesslingSafety of vaccines against zika and other flaviviruses01.12.2016 - 31.12.2023
Prof Dr Gerald G. SchumannSafety of human pluripotent stem cells in the use for somatic cell therapy01.01.2019 - 31.12.2021
Prof Dr van Ger ZandbergenEstablishment of an assessment system for innovative adjuvants01.07.2015 - 31.03.2020
Prof Dr Christian BuchholzStudies on acute side effects of CAR-T cells in mouse models01.11.2018 - 31.10.2022
Dr Michael MühlebachSafety and standardisation of measles vaccine strain derived vaccines against highly pathogenic bacteria01.11.2018 - 28.02.2022

BMBF | Federal Ministry of Education and Research

Project ManagerProject DescriptionDuration
Prof Dr von Veronika MesslingPEG-alternative polymers for bio-conjugation to proteins (Next-PEG) - subproject: safety and efficacy study of different interferon (IFN) alpha-2a conjugates01.08.2018 - 31.07.2021
Dr Christoph ConradDZIF | German Center for Infection Research: PDU CARB-X Accelerator: project management, consulting and regulatory aspects of antibiotic development01.01.2019 - 31.12.2021
Prof Dr Stefan ViethsDIFAMEM | Dietary intervention in food allergy: microbiome, epigenetic and metabolomic interactions 01.03.2019 - 28.02.2022
Prof Dr Isabelle Bekeredjian-DingAlternative methods to animal testing: B-CELL-ACT - functional test for B-cell activation by toxoid vaccines01.04.2019 - 31.03.2022
Dr. Verena Klümpers,
Dr. Micha Nübling,
Dr. Alexander Pinz
BISKIT | Blood Information System for Crisis Intervention and Management - Subproject: Processes and Structures01.04.2020 - 31.03.2023
Dr Nadine Kirsch-Stefan,
Dr Christoph Conrad
OSRA-PEI01.01.2021 - 28.02.2026
Dr Michael MühlebachJoint project | Emergency Vaccines PEI-TP: Recombinant measles virus vaccine platform01.01.2021 - 28.02.2026
Dr Bevan SawatskyDZIF | German Center for Infection Research: Animal facility for testing vaccines and antivirals against newly emerging infections under BSL 3/4 conditions01.02.2021 - 28.02.2026
Prof Dr Christian BuchholzCOMMUTE | (16GW0339) Drug delivery: combinatorial and multidisciplinary targeting of effective gene therapy vectors - rational design of receptor targeting AAV particles with DARPins01.03.2021 - 29.02.2024

DFG | German Research Foundation

Project ManagerProject DescriptionDuration
Dr Renate KönigInfluence on inflammation and DNA damage response and their effect on HIV-1 infection and tumor diseases01.01.2018 - 31.12.2021
Dr Stephan ScheurerImmune modulating mechanisms of flagellin A (FlaA)-fusion proteins at the interface between cell metabolism, TLR signaling, and inflammasome activation: WP2: TLR5/NLRC4-mediated activation01.03.2019 - 28.02.2022
Dr Stefan SchülkeImmune modulating mechanisms of flagellin A (FlaA)-fusion proteins at the interface between cell metabolism, TLR signaling, and inflammasome activation: WP1: Immune metabolism01.05.2019 - 30.04.2022
Dr Thorsten Jürgen MaierInvestigation of novel cysteine-reactive nitrofatty acids with covalent attack on inflammation-relevant drug targets01.11.2019 - 31.10.2022
Prof Dr Ralf R. Tönjes
Dr Antonia W. Godehardt
Biology of xenogenic cell, tissue and organ transplantation from basic research to clinical application01.07.2012 - 30.06.2024
Prof Dr Zoltán IvicsModeling of cerebellar pathology in ataxia-telangiectasia: study of ATM-deficient mice versus human iPS cells01.01.2020 - 31.12.2022
Prof Dr Ute ModlichHematopoietic stem cell-directed gene therapy for the treatment of ataxia telangiectasia (A-T)01.04.2020 - 31.03.2023
Prof Dr Ute ModlichEpcr expression and Epcr / Par1 signaling pathways in Mpl deficient and normal hematopoiesis during transplantation01.06.2020 - 31.05.2023
Prof Dr Ger van ZandbergenCell death dependence of the emergence of leishmania from infected host macrophages01.12.2020 - 30.11.2023
Dr Bevan Sawatsky
Dr Christian Pfaller
Intra- and inter-host dynamics and genetic plasticity of morbilliviruses01.01.2021 - 30.06.2021
Dr Renate KönigInvestigation of the cellular mechanisms of the PQBP1-mediated innate immune response to HIV-101.10.2020 - 30.09.2023

EU | European Union

Project ManagerProject DescriptionDuration
Dr Elisabeth Balks
Dr Andreas Reuter
Prof Dr Isabelle Bekeredjian-Ding
VAC2VAC | Vaccine batch to vaccine batch comparison by consistency testing01.03.2016 - 28.02.2022
Prof Dr von Veronika MesslingCrimean-Congo haemorrhagic fever vaccine (CCHFVaccine)01.01.2017 - 31.12.2022
Prof Dr Zoltan IvicsCARAMBA | SLAMF7-CAR T cells prepared by sleeping beauty gene-transfer for immunotherapy of multiple myeloma - a rare hematologic disease01.01.2018 - 30.04.2022
Priv-Doz Dr Dorothea Stahl
Birgit Haschberger
GAPP | Facilitating the authorisation of preparation process for blood and tissues and cells01.05.2018 - 31.01.2022
Bettina ZiegeleSTARS | Strengthening training of academia in regulatory sciences and supporting regulatory scientific advice01.01.2019 - 30.06.2022
Prof Dr Christian BuchholzSTACCATO | Enhancing the manufacture of advanced biological medicine through high-resolution analysis of single cells01.01.2019 - 31.12.2022
PD Dr. Benjamin HofnerEU-PEARL | Integrated research platforms enabling patient-centric drug development01.11.2019 - 30.04.2023
Prof Dr Zoe WaiblerimSAVAR | Emerging translational safety technologies and tools for interrogating human immuno-biology01.11.2019 - 31.10.2025
Prof Dr Isabelle Bekeredjian-DingCOMBINE | Collaboration for Prevention and Treatment of MDR Bacterial Infections01.11.2019 - 31.10.2025
Prof Dr Isabelle Bekeredjian-DingTIPAT | Training towards Personalized Antibiotic Treatment01.03.2020 - 29.02.2024
Prof Dr Zoltan Ivics
Prof Dr Christian Buchholz
T2EVOLVE | Accelerating Development and Improving Access to CAR and TCR-engineered T cell therapy01.01.2021 - 31.12.2025
Dr J. HartmannT-OP | Training Network for Optimizing Adoptive T cell Therapy of Cancer 01.03.2021 - 28.02.2025

LOEWE-Centres | State of Hesse

Project ManagerProject DescriptionDuration
Prof Dr Eberhard HildtLOEWE Center DRUID | Novel drug targets against poverty-related and neglected tropical infectious diseases: identification of target structures for the therapy of hepatitis E and C01.01.2018 - 31.12.2021
Prof Dr Eberhard Hildt
Dr Daniela Ploen
Dr Sally Baylis
LOEWE Center DRUID | Novel drug targets against poverty-related and neglected tropical infectious diseases: characterisation of the ZIKV/host interaction01.01.2018 - 31.12.2021
Prof Dr van Ger ZandbergenLOEWE Center DRUID | Novel drug targets against poverty-related and neglected tropical infectious diseases: W2 professorship for pathogen imaging and immunology01.01.2018 - 31.12.2021
Prof Dr van Ger ZandbergenLOEWE Center DRUID | Novel drug targets against poverty-related and neglected tropical infectious diseases: characterisation of apoptotic parasites to identify new target molecules for the treatment of leishmaniasis01.01.2018 - 31.12.2021
Prof Dr Barbara SchnierleLOEWE Center DRUID | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Implementation of a chikungunya virus vaccine candidate based on self-amplifying RNA01.10.2020 - 30.09.2021
Prof Dr Ger van ZandbergenLOEWE Center DRUID | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Parallel in vitro and in silico screening of small-molecule libraries against the key Leishmania enzyme glucose-6-phosphate dehydrogenase to identify first lead candidates01.07.2020 - 31.12.2021
Prof Dr Eberhard HildtLOEWE Center DRUID | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: cholesterol modulators efficiently block HEV replication01.07.2020 - 31.12.2021
Prof Dr Jacomina Krijnse LockerLOEWE Center DRUID | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Correlated light- and electron microscopy reveals virus entry and disassembly01.01.2020 - 31.12.2021
Prof Dr Jacomina Krijnse LockerLOEWE Center DRUID | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Cryo-correlated light- and electron microscopy using refrozen sections to study key events of host-pathogen interactions01.08.2021 - 31.12.2021
Prof Dr Eberhard HildtLOEWE Center DRUID | Novel Drug Targets against Poverty-Related and Neglected Tropical Infectious Diseases: Optimization and characterization of the antiviral potency of new cyclic Zika virus protease inhibitors in infected cells01.05.2021 - 30.04.2022

Various

BLE | Federal Office for Agriculture and Food

Project ManagerProject DescriptionDuration
Prof Dr Stefan Vieths
Dr Melanie Albrecht
ZeBaP | Development and validation of a cell-based test system for the detection of traces of allergens and for the determination of the allergenic potential of processed foods01.04.2020 - 31.03.2023
Dr Thomas HolzhauserDevelopment of an allergen-containing test biscuit for a special diet for babies - the food kiss (Solids-by-Kiss)01.01.2021 - 31.12.2023

CEPI | Coalition for Epidemic Preparedness Innovations

Project ManagerProject DescriptionDuration
Dr Michael MühlebachComparison of measles vectors in a murine model14.12.2018 - 30.06.2021
Dr Michael MühlebachMV-MERS PEI Project 3 - Correlates of protection of MERS01.04.2021 - 30.09.2021

CSC | China Scholarship Council

Project ManagerProject DescriptionDuration
Prof Dr Eberhard HildtGrant Qingyan Wu: Comaptative analysis of entry and release parameters for HBV09.10.2017 - 08.10.2021

DAAD | German Academic Exchange Service

Project ManagerProject DescriptionDuration
Prof Dr Eberhard HildtGrant Sara Mohamed: Turnover of nonstructural proteins in HCV life cycle01.12.2017 - 30.09.2021

DGUV | German Statutory Accident Insurance

Project ManagerProject DescriptionDuration
Prof. Dr. Vera Mahler  Quality assurance of the diagnosis of occupational type I allergies01.11.2020 - 31.10.2023

EDQM | European Directorate for the Quality of Medicine

Project ManagerProject DescriptionDuration
Prof Dr Stefan ViethsRecombinant major allergens (BRPs and assay methods)undetermined

FEI | Research Association of the German Food Industry

Project ManagerProject DescriptionDuration
Prof Dr Stefan Vieths
Dr Stephan Scheurer
Examination of the health-promoting effect of pectins in food allergies01.04.2019 - 31.03.2022

German Cancer Aid

Project ManagerProject DescriptionDuration
Prof Dr Christian BuchholzIn vivo generation of CAR T cells in an immunocompetent large animal model01.06.2021 - 31.05.2024

Health Holland

Project ManagerProject DescriptionDuration
Prof Dr Christian BuchholzLentiviral biological pacemakers01.03.2020 - 28.02.2022

Innovation Committee of the Joint Federal Committee

Project ManagerProject DescriptionDuration
Dr Brigitte Keller-StanislawskiFeasibility study on the suitability of different data sources as a basis for improving pharmacovigilance of innovative therapies using multiple sclerosis as an example01.06.2019 - 31.05.2022

ISBT | International Society of Blood Transfusion

Project ManagerProject DescriptionDuration
Dr Marcel PraxEstablishment of platelet bacterial reference strains in BioBall formatfrom 2019

NIH | National Institut of Health

Project ManagerProject DescriptionDuration
Prof Dr Christian BuchholzDisabling the replication-competent HIV provirus in the reservoir by combined CRISPR-Cas action05.04.2019 - 05.04.2023

Rudolf Marx Foundation

Project ManagerProject DescriptionDuration
Prof Dr Ger van Zandbergen
Prof Dr Jacomine Krijnse Locker
Studies on the influence of a2-macroglobulin on the infectivity of SARS-CoV-2 in cell cultureindefinite

SEAIC | Spanish Society of Allergy Clinical Immunology

Project ManagerProject DescriptionDuration
Dr Stephan ScheurerGrant Dr Laura Pedraza: Role of peach tree pollen allergen Pru p 9 and its modification by glycosylation in the interaction with the immune system and its involvement in peach allergyindefinite

Updated: 31.05.2021