Paul-Ehrlich-Institut

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Re­search in the Vi­rol­o­gy Di­vi­sion

Infection with Hepatitis C Viruses (Source: E.Hildt/Paul-Ehrlich-Institut)

Research Focus

This division conducts research related to official testing duties on the efficacy and safety of vaccines and on the detailed characterisation of the immune response after vaccination or infection. Another essential focus of the division is its research into broadly effective antiviral strategies, conducted by modulating the innate immune response in order to efficiently inhibit the proliferation of novel pandemic pathogens.

The Virology Division also researches the life cycle and virus-associated pathogenesis of various hepatitis viruses in order to develop antiviral and therapeutic strategies for chronic infections.

Intracellular distribution in a three-dimensional reconstruction of the hepatitis C virus proteins NS3 or the hepatitis C virus nucleus (core, green) and the cellular proteins LAMP2 (cyan) and GBP1 (red). (Source: Paul-Ehrlich-Institut) Intracellular distribution in a three-dimensional reconstruction of the hepatitis C virus proteins NS3 or the hepatitis C virus nucleus (core, green) and the cellular proteins LAMP2 (cyan) and GBP1 (red). Source: Paul-Ehrlich-Institut

Research Group Head

Prof Dr Eberhard Hildt
Publications
Phone: +49 6103 77 2140
Email: Eberhard.Hildt@pei.de

Research Projects

Research projects related to testing

  • Characterisation of the immune response after vaccination and/or infection
  • Development of a customisable vaccine platform for preventive and therapeutic vaccinations

Research projects on hepatitis viruses

  • Build broad antiviral response by modulating innate immune response

Updated: 04.09.2023