Paul-Ehrlich-Institut

Information on the Use of Cookies

In order to operate and optimise our website, we would like to collect and analyse statistical information completely anonymously. Will you accept the temporary use of statistics cookies?

You can revoke your consent at any time in our privacy policy.

OK

Publications in 1998

Please note: Authors from the Paul-Ehrlich-Institut are highlighted in bold. For online abstracts or full text publications, please follow the links.

Adorini L, Goldmann M, Kabelitz D, Revillard JP, Waldmann H (1998): Apoptosis, tolerance, and immunoregulation - Integrated pathways for immune system homeostasis.
The Immunologist 6: 92-94.

Arden B, Weber-Arden J, Wilbert OM, Kabelitz D (1998): TCRd rearrangement is confined to the proximal cluster of Va gene segments.
Immunobiol. 199: 469.

Baier M, Bannert N, Werner A, Adler HS, Otteken A, Beer B, Norley S, Kurth R (1998): Chemoattractant Factors and the Control of Human Immunodeficiency Virus Replication.
Pathobiology 66: 128-130.
Online-Abstract

Bannert N, Adler HS, Werner A, Baier M, Kurth R (1998): Molecular Cloning and Sequence Analysis of Interleukin 16 from Nonhuman Primates and from the Mouse.
Immunogenetics 47: 390-397.
Online-Abstract

Beer B, Denner J, Brown CR, Norley S, zur Megede J, Coulibaly C, Plesker R, Holzammer S, Baier M, Hirsch VM, Kurth R (1998): Simian Immunodeficiency Virus of African Green Monkeys is Apathogenic in the Newborn Natural Host.
JAIDS 18: 210-220.
Online-Abstract

Blum SA, Braunschweiger M, Krämer B, Rübmann P, Duchow K, Cußler K (1998): Nachweis der vollständigen Virusinaktivierung bei Tollwut-Impfstoffen. Ein in vivo- in vitro-Vergleich.
Altex 15: 46-49.
Online-Abstract

Buchholz CJ, Peng KW, Morling FJ, Zhang J, Cosset FL, Russell SJ (1998): In vivo selection of protease cleavage sites from retrovirus display libraries.
Nat Biotechnol 16: 951-954.
Online-Abstract

Conrad C, Kabelitz D, Schäffner G (1998): Wirksamkeitsprüfung von Antilymphozytenseren: Entwicklung von in vitro Methoden als Ersatz des Affenhaut-Transplantationstests.
Altex 15: 27-30.
Online-Abstract

Cußler K, Morton D, Hendriksen CFM (1998): Klinische Endpunkte als Ersatz für die Bestimmung der Letalistätsrate bei Tollwutinfektionsversuchen zur Impfstoffprüfung.
Altex 15: 40-42.
Online-Abstract

Dobmeyer TS, Dobmeyer JM, Klein SA, Wagner S, Helm EB, Hoelzer D, Rossol R, Kabelitz D (1998): Mechanism of gd T-cell mediated inhibition of stem cell differentiation in vitro: Possible relevance for myelosuppression in HIV-infected individuals.
Cell. Immunol 184: 26-36.
Online-Abstract

Dobmeyer TS, Klein SA, Dobmeyer JM, Raffel B, Markert BR, Hoelzer D, Helm EB, Rossol R, Kabelitz D (1998): Differential expression of bcl-2 and susceptibility to programmed cell death in lymphocytes of HIV-1 infected individuals.
Clin. Immunol. Immunopathol 87: 230-239.
Online-Abstract

Doll M, Salge U, Kleiner K, Lorenz M, Seitz R, Heiden M (1998): Oxidative alteration of blood coagulation in methylene blue-treated therapeutic plasma. 42nd Annual Meeting of the GTH, Frankfurt/Main, February 25-28.
Annals of Hematology 76: A64.

Ebert E, Abu Karim A, Kayser T, Wenig R, Weißer KM, Wirz M, Pisani G, Schäffner G, Cußler K (1998): Optimierung und Etablierung von serologischen Methoden für die Wirksamkeitsprüfung von Immunblobulinen gegen Clostridium tetani-Toxoid.
Altex 15: 30-32.
Online-Abstract

Ebert E, Öppling V, Werner E, Cußler K (1998): Development and prevalidation of alternative methods for the potency testing of C. perfringens vaccines.
Altex 15: 59-61.
Online-Abstract

Ebrecht A, Patscheke H (1998): Prevalence of blood coagulation factor V mutation LEIDEN in dependency of age, sex, D-Dimer concentration and the activities of AT III, Protein C and Protein S. 42nd Annual Meeting of the GTH, Frankfurt/Main, February 25-28.
Annals of Hematology 76: A78.

Eich S, Grundmann C, Seitz R, König H (1998): Highly sensitive in vitro assay for FVIIa: Application for the analysis of therapeutical blood products. 42nd Annual Meeting of the GTH, Frankfurt/Main, February 25-28.
Annals of Hematology 76: A50.

Etscheid M, Riesner D: TGGE and DGGE.
Karp A, Issac PG, Ingram DS (Hrsg.), Molecular Tools for Screening Biodiversity, Plants and animals London: Chapman and Hall, 1998. 135-151 ISBN 0-412-63830-4

Falkenbach A, Sedlmeyer A, Unkelbach U (1998): UVB radiation and its role in the treatment of postmenopausal women with osteoporosis.
Internat. J. of Biometeorology 41: 128.
Online-Abstract

Fennrich S, Fischer M, Hartung T, Lexa P, Montag-Lessing T, Sonntag HG, Weigandt M, Wendel A (1998): Evaluation and further development of a pyrogenicity assay based on human whole blood.
ALTEX 15: 123-128.
Online-Abstract

Fennrich S, Fischer M, Hartung T, Lexa P, Montag-Lessing T, Sonntag HG, Weigandt M, Wendel A (1999): Detection of endotoxins and other pyrogens using human whole blood.
Dev Biol Stand 101: 131-9.
Online-Abstract

Fischer M, Hartzsch K, Hartung T, Montag-Lessing T (1998): Erste Erfahrungen bei der Prävalidierung des Vollblutpyrogentests für biologische Arzneimittel.
Altex 15: 10-13.
Online-Abstract

Flory E, Weber C, Chen P, Hoffmeyer A, Jassoy C, Rapp UR (1998): Plasma membrane-targeted Raf Kinase Activates NF-kB and Human Immunodeficiency Virus -1 replication in T Lymphocytes.
J. Virol 72: 2788-2794.
Online-Abstract

Fötisch K, Fäh J, Wüthrich B, Altmann F, Haustein D, Vieths S (1998): IgE antibodies specific for carbohydrates in a patient allergic to gum arabic (Acacia senegal).
Allergy 53: 1043-1051.

Frey T, Ebrecht A, Neugebauer B, Schörner-Burkhardt E, Goy C, Budek I, Seitz R (1998): Characterisation of Coagulation Factor VIII-Concentrates with regard to integrity of Factor VIII and von Willebrand Factor (Intern. Congress of the World Federation of Hemophilia, Den Haag, 17.-20.05.98).
Haemophilia 4.

Hartinger J, Matheis W (1998): Steckbriefe immunologischer Adjuvantien: II Aluminium-Gele.
Der Tierschutzbeauftragte: 47-48.

Hartung T, Fennrich S, Fischer M, Montag-Lessing T, Wendel A (1998): Development and evaluation of a pyrogen test based on human whole blood.
ALTEX 15: 9-10.
Online-Abstract

Hauses M, Tönjes RR, Grez M (1998): The transcription factor Sp1 regulates the myeloid-specific expression of the human hematopoietic cell kinase (hck) gene through binding to two adjacent GC-boxes within the HCK promoter-proximal region.
J Biol Chem 273: 31844-31852.
Online-Abstract

Hinz T, Allam A, Wesch D, Schindler D, Kabelitz D (1998): Chimaeric T cell receptors in Ataxia telangiectasia patients and healthy individuals.
Immunobiol 199: 616-617.

Holst FGE, Hemmer CJ, Foth C, Seitz R, Egbring R, Dietrich M (1998): Low levels of Fibrin Stabilizing Factor (FactorXIII) in Human Plasmodium Falciparum Malaria correlate with clinical severirty.
Am J Trop Med Hyg.

Holzhauser T, Dehne LI, Hoffmann A, Haustein D, Vieths S (1998): Rocket immunoelectrophoresis (RIE) for determination of potentially allergenic peanut proteins in processed foods as a simple means for quality assurance and food safety.
Z Lebensm Unters Forsch A 206: 1-8.
Online-Abstract

Hunfeld A, Etscheid M, König H, Seitz R, Dodt J (1998): Identification of the thrombin-like activity of PCCs. 42nd Annual Meeting of the GTH, Frankfurt/Main, February 25-28.
Annals of Hematology 76: A101.

Jankiewicz A, Aulepp H, Altmann F, Fötisch K, Vieths S (1998): Serological investigation of 30 celery-allergic patients with particular consideration of the thermal stability of IgE binding celery allergens.
Allergo J 7: 87-95.

Johannes S, Rosskopf-Streicher U, Hausleithner D, Gyra H, Cussler K (1998): Proposal for a standard method for pig challenge tests with erysipelas strains.
Pharmeuropa BIO, Proceedings of the Symposium: Alternatives to animal test in the development and control of erysipelas vaccines, December 1998: 40-44.

Johannes S, Rosskopf-Streicher U, Hausleithner D, Gyra H, Cussler K: Use of clinical signs in efficacy testing of erysipelas vaccines.
In: Hendriksen CFM, Morton DB (eds.), Humane Endpoints in Animal Experiments for Biomedical Research: Proceedings of the International Conference, 22-25 November 1998 Zeist, Netherlands. London: The Royal Society of Medicine Press Limited, 1998. 102-105. ISBN 1-85315-429-6

Kabelitz D (1998): T-Lymphozyten bei der Immunabwehr.
Target Forum 1: 30-36.

Kabelitz D (1998): Apoptosis, graft rejection and transplantation tolerance.
Transplantation 65: 869-875.

Kastrati A, Schömig A, Elezi S, Schühlen H, Wilhelm MG, Dirschinger J (1998): Interlesion dependence of the risk for restenosis in patients with coronary stent placement in multiple lesions.
Circulation 97: 2396-2401.
Online-Abstract

Kaufmann SHE, Kabelitz D: The immune response to infectious agents.
Kaufmann SHE, KabelitzD (Hrsg.), Methods in Microbiology: Immunology of Infection London: Academic Press. 1-19 ISBN 0-12-521528-2

Kaul A, Nübling CM, Kempfer M, Schmidt I, Löwer J (1998): Entwicklung von molekularbiologischen Alternativmethoden zur Prüfung von Poliomyelitis-Impfstoffen.
ALTEX 15: 18-20.
Online-Abstract

Keller G, Rudelius M, Vogelsang H, Grimm V, Wilhelm MG, Mueller J, Siewert JR, Höfler H (1998): Microsatellite instability and loss of heterozygosity in gastric carcinoma in comparison to family history.
Am J Pathol 152: 1281-1289.
Online-Abstract

Klein K, Anduleit M, Bornhak M, Fischer M, Gross U, Löschner B, Nicol S, Reiter-Orwona I, Zyto N, Montag-Lessing T (1998): Vergleichende Charakterisierung von Toxoplasma gondii-Tachyzoiten aus unterschiedlichen Kultivierungsverfahren.
ALTEX 15: 37-39.
Online-Abstract

Krämer B, Rübmann PK, Duchow K, Cußler K (1998): Fremdvirusausschluß in Lebendimpfstoffen.
ALTEX 15: 43-45.
Online-Abstract

Kraft M, Filsinger S, Krämer KL, Kabelitz D, Hänsch GM, Schoels M (1998): Synovial fibroblasts as target cells for staphylococcal enterotoxin induced T-cell cytotoxicity.
Immunology 93: 20.
Online-Abstract

Kusch M, Rübmann P, Seitz R, König H (1998): Highly sensitive in vitro assay for FIXa: Its use in biochemical and molecular characterization. 42nd Annual Meeting of the GTH, Frankfurt/Main, February 25-28.
Annals of Hematology 76: A17.

Kusch M, Seitz R, König H (1998): Highly sensitive in vitro assay for FIXa II:Application for the analysis of therapeutical FIX concentrates. 42nd Annual Meeting of the GTH, Frankfurt/Main, February 25-28.
Ann Hematol 76: A51.

Kusch M, Seitz R, König H (1998): High Sensitivity Detection of Activated Factor IX: Application to the Analysis of Different Therapeutical Factor IX Concentrates and Prothrombin Complexes.
Thromb Haemost 79: 778-783.
Online-Abstract

Langhardt A, Frank L, Küchler B, Jungbäck C (1998): Die Aviäre Enzephalomyelitits des Huhnes: Beitrag zur Reduktion der Tierzahlen bei der Impfstoffprüfung.
ALTEX 15: 49-52.
Online-Abstract

Löwer R, Tönjes RR, Boller K, Denner J, Kaiser B, Phelps RC, Löwer J, Kurth R, Badenhoop K, Donner K, Usadsel KH, Miethke T, Lapatschek M, Wagner H (1998): Development of insulin-dependent diabetes mellitus does not depend on specific expression of the human endogenous retrovirus HERV-K.
Cell 95: 11-14.
Online-Abstract

Mühlhan P, Zweckstetter M, Georgescu J, Ciosto C, Renner C, Lanzendörfer M, Lang K, Ambrosius D, Baier M, Kurth R, Holak TA (1998): Structure of interleukin 16 resembles a PDZ domain with an occluded peptide binding site.
Nature Structural Biology 5: 682-686.
Online-Abstract

Müller P, Dittmar MT, Beer B, König R, Plesker R, Norley S, Kurth R, Cichutek K (1998): Increased serum and mRNA levels of MIP-1b and RANTES associated with elevated levels of activated CD8+CD38+ T-cells in HIV-1 infected individuals.
Intervirology.

Müller U, Weber W, Hoffmann A, Franke S, Lange R, Vieths S (1998): Commercial soybean lecithins: A source of hidden allergens?.
Z Lebensm Unters Forsch A 207: 341-351.
Online-Abstract

Nübling CM, Gröner A, Löwer J (1998): GB Virus C / Hepatitis G Virus and intravenous immunoglobulins.
Vox Sanguinis 75: 189-192.
Online-Abstract

Neugebauer BM, Frey T, Seitz R, Budek I: Characterisation of Blood Clotting Factor VIII Concentrates.
In: Scharrer I, Schramm W (Hrsg.), 27. Hämophilie-Symposium Hamburg 1996. Berlin, Heidelberg: Springer, 1998. 293-302.

Neugebauer B, Nawrot R, Jescheck C, Budek I (1998): Overview of Blood Clotting Factor VIII (FVIII) Concentrates on the German Market. (Intern. Congress of the World Federation of Hemophilia, Den Haag, 17.-20.05.98).
Haemophilia 4.

Niggemann B, Kleine-Tebbe J, Saloga J, Sennekamp J, Vieluf J, Vieths S, Werfel T, Jäger L (1998): DGAI-Positionspapier: Standardisierung von oralen Provokationstests bei IgE-vermittelten Nahrungsmittelallergien.
Allergo J 7: 45-50.

Nilsson C, Makitalo B, Thorstensson R, Norley S, Binninger-Schinzel D, Cranage M, Rud E, Biberfeld G, Putkonen P (1998): Live Attenuated Simian Immunodeficiency Virus (SIV)mac in Macaques can Induce Protection Against Mucosal Infection with SIVsm.
AIDS 12: 2261-70.
Online-Abstract

Nübling CM (1998): HCV-NAT in der Transfusionsmedizin - Hintergrund, Anforderungen, Validierung.
Hygiene und Mikrobiologie 3: 9-11.

Nübling CM (1998): HCV-NAT in der Transfusionsmedizin - Hintergrund, Anforderungen, Validierung.
Hygiene und Mikrobiologie.

Nübling CM, Löwer J: GB-C / Hepatitis G Virus bei Hämophilen, Dialysepatienten, HIV-Infizierten und sein Nachweis in Blutprodukten.
Scharrer I, Schramm W (Hrsg.), 27. Hämophilie-Symposion Hamburg 1996 Berlin, Heidelberg: Springer, 1998. 47-53 ISBN 3-540-62915-7

Nübling CM, Seitz R, Löwer J (1998): Application of Nucleic Acid Amplification Techniques for Blood Donation Screening.
Infusion Therapy and Transfusion Medicin 25: 86-90.
Online-Abstract

Pechhold K, Kabelitz D: Measurement of cellular proliferation (3H-thymidine uptake, MTT, absolute cell numbers by SCDA).
Kaufmann SHE Kabelitz D (Hrsg.), Methods in Microbiology: Immunology of Infection: Academic Press, 1998. 59-78

Pößnecker A, Cußler K (1998): Untersuchungen zur Relevanz der Prüfung auf spezifische Unschädlichketi an der Zieltierspezies. Ergebnisse bei bakteriellen Impfstoffen im Zeitraum vno 1994-1997.
ALTEX 15: 71-75.
Online-Abstract

Revillard JP, Adorini L, Goldman M, Kabelitz D, Waldman H (1998): Apoptosis: Potential for disease therapies.
Immunol. Today 19: 291-293.
Online-Abstract

Rosskopf-Streicher U, Johannes S, Hausleithner D, Gyra H, Cussler K (1998): Suitability of an Elisa for the batch potency test in laboratory mice.
Pharmeuropa BIO 1: 65-70.

Rossol R, Dobmeyer JM, Dobmeyer TS, Klein SA, Rossol S, Wesch D, Hoelzer D, Kabelitz D, Helm EB (1998): Increase in Vd1+ gd T-cells in the peripheral blood and bone marrow as a selective feature of HIV-1 but not other virus infections.
Brit. J. Haematol 100: 728-34.
Online-Abstract

Salge U, Daubner E, Heiden M, Wilhelm M, Hommann M, Weinel W, Seitz R (1998): Studies on Coagulation and Fibrinolysis Markers in Patients with Hepato Cellular Carcinoma and Pancreatic Cancer. 42nd Annual Meeting of the GTH, Frankfurt/Main, February 25-28.
Annals of Hematology 76: A46.

Sanzenmacher R, Kabelitz D, Janssen O (1998): p56lck/SLP-76 complex formation and functional interaction in TCR desensitization and inhibition of AICD.
Immunobiol 199: 469.

Schulz H, Karau A, Filsinger S, Schoels M, Kabelitz D, Richter R, Hänsch GM (1998): Tubular epithelial cells as accessory cells for superantigen-induced T-cell activation.
Exp. Nephrol 6: 67-73.

Schwanig M (1998): Ersatzmethoden zum Tierversuch. Der lange Weg von der Entwicklung bis zur Arzneibuchmethode.
ALTEX 15: 6-9.
Online-Abstract

Seitz R, Burger R, Gerlich W, Gürtler L, Heiden M, Kretschmer V, Lefèvre H, Löwer J, Montag-Lessing T, Neumann R, Pauli G, Schlenkrich U, Werner E, Willkommen H, Schreier E, Nübling M (1998): GB-Virus Typ C (GBV-C), Andere Bezeichnung: Hepatitis-G-Virus (HGV).
Bundesgesundheitsbl. 41: 88-90.

Seitz R, Burger R, Gerlich W, Gürtler L, Heiden M, Kretschmer V, Lefèvre H, Löwer J, Montag-Lessing T, Neumann R, Pauli G, Schlenkrich U, Werner E, Willkommen H (1998): Humane T-Zell lmphotrophe Viruse Typ 1 und 2 (HTLV-I/-II).
Bundesgesundheitsbl 41: 512-517.

Seitz R, Burger R, Gerlich W, Gürtler L, Heiden M, Kretschmer V, Lefèvre H, Löwer J, Montag-Lessing T, Neumann R, Pauli G, Schlenkrich U, Werner E, Willkommen H (1998): Parvovirus B19.
Bundesgesundheitsbl. 41: 83-87.

Seitz R, Burger R, Gerlich W, Gürtler L, Heiden M, Kretschmer V, Lefèvre H, Löwer J, Montag-Lessing T, Neumann R, Pauli G, Schlenkrich U, Werner E, Willkommen H (1998): Creutzfeld-Jakob-Erkrankung (CJK) bzw. humane übertragbare (transmissible) spongiforme Enzephalopathien (TSE).
Bundesgesundheitsbl 41: 78-83.

Seitz R, Burger R, Gerlich W, Gürtler L, Heiden M, Kretschmer V, Lefèvre H, Löwer J, Montag-Lessing T, Neumann R, Pauli G, Schlenkrich U, Werner E, Willkommen H (1998): Parvovirus B19.
Infusther Transfusionsmed 25: 97-102.
Online-Abstract

Seitz R, Burger R, Gerlich W, Gürtler L, Heiden M, Kretschmer V, Lefèvre H, Löwer J, Montag-Lessing T, Neumann R, Pauli G, Schlenkrich U, Werner E, Willkommen H (1998): Creutzfeld-Jakob Disease and Human Transmissible Spongiform Encephalopathies.
Infusionsther Transfusionsmed 25: 89-96.

Seitz R, Burger R, Gerlich W, Gürtler L, Heiden M, Kretschmer V, Lefèvre H, Löwer J, Montag-Lessing T, Neumann R, Pauli G, Schlenkrich U, Werner E, Willkommen H (1998): GB-Virus Typ C (GBV-C), Alternative Denomination Hepatitis-G-Virus (HGV).
Infusther Transfsionsmed 25: 103-106.
Online-Abstract

Seitz R, Burger R (1998): Assessment of Pathogens Transmissible by Blood.
Infusionsther Transfusionsmed 25: 88.
Online-Abstract

Seitz R, Burger R (1998): Science, Lawyers and „the Europeans": Testing Requirements in Transfusion Medicine (Leserbrief).
Transfusion 38: 506-507.

Stitz J, Müller P, Cichutek K (1998): High-titer retroviral pseudotype vectors for specific targeting of human CD4-positive cells.
Biogenic Amines 14: 407-424.

Stöcker S, Heiden M, Seitz R (1998): Bluttransfusionen - Auf absehbare Zeit nicht zu ersetzen. (Leserbrief).
Dtsch Apoth Ztg 138.

Tönjes RR (1998): Diabetes und Superantigene.
Spektrum der Wissenschaft 2: 28-30.

Van Buul C, Cuypers H, Lelie P, Chudy M, Nübling CM, Melsert R, Oudshoorn P (1998): The NucliSenstm Extractor.
Infusionstherapie und Transfusionsmedizin 25: 147-151.

Vieths S, Frank E, Scheurer S, Meyer HE, Hrazdina G, Haustein D (1998): Characterisation of a new IgE-binding 35-kDa protein from birch pollen with cross-reacting homologues in various plant foods.
Scand J Immunol 47: 263-272.
Online-Abstract

Vieths S, Hoffmann A, Holzhauser T, Müller U, Reindl J, Haustein D (1998): Factors influencing the quality of food extracts for in vitro and in vivo diagnosis.
Allergy 53: 65-71.

Vieths S, Jankewiecz A, Holzhauser T: Charakterisierung von Allergenen und Nachweis potentiell allergener Bestandteile in verarbeiteten Lebensmitteln.
In: Borsdorf R, Lüdewald I, Wisser H (Hrsg.), Berlin: Springer, 1998. S. 3-44
(Analytiker Taschenbuch; 20)

Vieths S, May S, Haustein D (1998): Qualität von Allergenextrakten.
Bundesgesundhbl 41: 12-17.

Wagener S, Dittmar MT, Beer B, König R, Plesker R, Norley S, Kurth R, Cichutek K (1998): The U3 Promoter and the nef Gene of Simian Immunodeficiency Virus (SIV) smmPBj1.9 Do Not Confer Acute Pathogenicity upon SIVagm.
J. Virol 72: 3446-3450.

Wegener M, Bruckner L, Cußler K (1998): The establishment of endotoxin limits which satisfy animal welfare considerations in the testing of porcine vaccines.
Altex 15: 65-67.
Online-Abstract

Wesch D, Hinz T, Kabelitz D (1998): Analysis of the T cell receptor Vg repertoire in healthy donors and HIV-1 infected individuals.
Int. Immunol 10: 1067-1075.
Online-Abstract

Wesch D, Marx S, Kabelitz D (1998): Monocyte dependent death of freshly isolated T lymphocytes: Induction by phorbolester and mitogens and differential effects of catalase.
J. Immunol 161: 1248-1256.

Zwerger C, Plesker P, Papadopulos K, Cußler K, Hartinger J (1998): Vergleich kommerziell erhältlicher Adjuvantien bei BALB/c-Mäusen mit einem schwach immunogenen Peptid als Antigen.
Altex 15: 83-86.
Online-Abstract