Paul-Ehrlich-Institut

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Publications in 2021

Please note: Authors from the Paul-Ehrlich-Institut are highlighted in bold. For online abstracts or full text publications, please follow the links.

Aganovic K, Hertel C, Vogel RF, Johne R, Schlüter O, Schwarzenbolz U, Jäger H, Holzhauser T, Bergmair J, Roth A, Sevenich R, Bandick N, Kulling SE, Knorr D, Engel KH, Heinz V (2021): Aspects of high hydrostatic pressure food processing: Perspectives on technology and food safety.
Compr Rev Food Sci Food Saf 20: 3225-3266.
Online-Abstract

Albinger N, Hartmann J, Ullrich E (2021): Current status and perspective of CAR-T and CAR-NK cell therapy trials in Germany.
Gene Ther 28: 513-527.
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Albrecht M (2021): Turning off the alarm - Targeting alarmins and other epithelial mediators of allergic inflammation with biologics.
Allergol Select 9: 82-88.
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Ansah JK, Kafere C, Loua A, Nkansah E, Acquah ME, Mudyiwenyama L (2021): Regulation of blood services in Africa.
Transfus Clin Biol 28: 148-153.
Online-Abstract

Anzaghe M, Kronhart S, Niles MA, Höcker L, Dominguez M, Kochs G, Waibler Z (2021): Type I interferon receptor-independent interferon-α induction upon infection with a variety of negative-strand RNA viruses.
J Gen Virol 102: 001616.
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Araujo-Fernandez I, Delgado J, Moscetti L, Sarac SB, Zander H, Müller-Egert S, Dunder K, Pean E, Bergmann L, Enzmann H, Pignatti F (2021): The European Medicines Agency review of the initial application of atezolizumab and the role of PD-L1 expression as biomarker for checkpoint inhibitors.
ESMO Open 6: 100008.
Online-Abstract

Basic M, Kubesch A, Kuhnhenn L, Görgülü E, Finkelmeier F, Dietz J, Knabe M, Mücke VT, Mücke MM, Berger A, Zeuzem S, Sarrazin C, Hildt E, Peiffer KH (2021): Not uncommon: HBV genotype G co-infections among healthy European HBV carriers with genotype A and E infection.
Liver Int 41: 1278-1289.
Online-Abstract

Baylis S, Nübling CM, Dimech W: Standardization of diagnostic assays.
In: Bamford DH, Zuckerman M (Hrsg.), Encyclopedia of Virology (Fourth Edition): Academic Press, 2021. S. 52-63, ISBN 978-0-12-814516-6

Baylis SA, Nübling CM (2021): Nucleic Acid Testing of Viral Pathogens: Traceability of the International Unit.
Clin Chem 68: 257-258.
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Bitar L, Schumann U, König R, Zipp F, Schmidt MHH (2021): Targeting Immune Modulators in Glioma While Avoiding Autoimmune Conditions.
Cancers (Basel) 13: 3524.
Online-Abstract

Blanco-Pérez F, Steigerwald H, Schülke S, Vieths S, Toda M, Scheurer S (2021): The Dietary Fiber Pectin: Health Benefits and Potential for the Treatment of Allergies by Modulation of Gut Microbiota.
Curr Allergy Asthma Rep 21: 43.
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Bousquet J, Agache I, Blain H, Jutel M, Ventura MT, Worm M, Del Giacco S, Benetos A, Bilo MB, Czarlewski W, Abdul Latiff AH, Al-Ahmad M, Angier E, Annesi-Maesano I, Atanaskovic-Markovic M, Bachert C, Barbaud A, Bedbrook A, Bennoor KS, Berghea EC, Bindslev-Jensen C, Bonini S, Bosnic-Anticevich S, Brockow K, Brussino L, Camargos P, Canonica GW, Cardona V, Carreiro-Martins P, Carriazo A, Casale T, Caubet JC, Cecchi L, Cherubini A, Christoff G, Chu DK, Cruz AA, Dokic D, El-Gamal Y, Ebisawa M, Eberlein B, Farrell J, Fernandez-Rivas M, Fokkens WJ , Fonseca JA, Gao Y, Gavazzi G, Gawlik R, Gelincik A , Gemicioğlu B, Gotua M, Guérin O, Haahtela T, Hoffmann-Sommergruber K, Hoffmann HJ, Hofmann M, Hrubisko M, lenaIllario M, Irani C, Ispayeva Z, Ivancevich JC, Julge K, Kaidashev I, Khaitov M, Knol E, Kraxner H, Kuna P, Kvedariene V, Lauerma A, Le LT, Le Moing V, Levin M, Louis R, Lourenco O, Mahler V, Martin FC, Matucci A, Milenkovic B, Miot S, Montella E, Morais-Almeida M, Mortz CG, Mullol J, Namazova-Baranova L, Neffen H, Nekam K, Niedoszytko M, Odemyr M, O'Hehir RE, Okamoto Y, Ollert M, Palomares O, Papadopoulos NG, Panzner P, Passalacqua G, Patella V, Petrovic M, Pfaar O, Pham-Thi N, Plavec D, Popov TA, Recto MT, Regateiro FS, Reynes J , Roller-Winsberger RE, Rolland Y, Romano A, Rondon C, Rottem M, Rouadi PW, Salles N, Samolinski B, Santos AF, Serpa FS, Sastre J, Schols JMGA, Scichilone N, Sediva A, Shamji MH, Sheikh A, Skypala I, Smolinska S, Sokolowska M, Sousa-Pinto B, Sova M, Stelmach R, Sturm G, Suppli Ulrik C, Todo-Bom AM, Toppila-Salmi S, Tsiligianni I, Torres M, Untersmayr E, Urrutia Pereira M, Valiulis A, Vitte J, Vultaggio A, Wallace D, Walusiak-Skorupa J, Wang DY , Waserman S, Yorgancioglu A, Yusuf OM, Zernotti M, Zidarn M, Chivato T, Akdis CA, Zuberbier T, Klimek L (2021): Management of anaphylaxis due to COVID-19 vaccines in the elderly.
Allergy 76: 2952-2964.
Online-Abstract

Büning H, Fehse B, Ivics Z, Kochanek S, Koehl U, Kupatt C, Mussolino C, Nettelbeck DM, Schambach A, Uckert W, Wagner E, Cathomen T (2021): Gene Therapy "Made in Germany": A Historical Perspective, Analysis of the Status Quo, and Recommendations for Action by the German Society for Gene Therapy.
Hum Gene Ther 32: 987-996.
Online-Abstract

Bueno-Díaz C, Martín-Pedraza L, Parrón J, Cuesta-Herranz J, Cabanillas B, Pastor-Vargas C, Batanero E, Villalba M (2021): Characterization of Relevant Biomarkers for the Diagnosis of Food Allergies: An Overview of the 2S Albumin Family.
Foods 10: 1235.
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Canet-Pons J, Sen NE, Arsovíc A, Almaguer-Mederos LE, Halbach MV, Key J, Döring C, Kerksiek A, Picchiarelli G, Cassel R, René F, Dieterlé S, Fuchs NV, König R, Dupuis L, Lütjohann D, Gispert S, Auburger G (2021): Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression.
Neurobiol Dis 152: 105289.
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Chansard A, Dubrulle N, Poujol de Molliens M, Falanga PB, Stephen T, Hasan M, van Zandbergen G, Aulner N, Shorte SL, David-Watine B, Milieu Intérieur Consortium (2021): Corrigendum: Unveiling Interindividual Variability of Human Fibroblast Innate Immune Response Using Robust Cell-Based Protocols.
Front Immunol 12: 685768.
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Chansard A, Dubrulle N, Poujol de Molliens M, Falanga PB, Stephen T, Hasan M, van Zandbergen G, Aulner N, Shorte SL, David-Watine B (2021): Unveiling Interindividual Variability of Human Fibroblast Innate Immune Response Using Robust Cell-Based Protocols.
Front Immunol 11: 569331.
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Chanyalew M, Abebe M, Endale B, Girma S, Tasew G, Bobosha K, Zewide M, Howe R, van Zandbergen G, Ritter U, Gadisa E, Aseffa A, Laskay T (2021): Enhanced activation of blood neutrophils and monocytes in patients with Ethiopian localized cutaneous leishmaniasis in response to Leishmania aethiopica Neutrophil activation in Ethiopian cutaneous leishmaniasis.
Acta Trop 220: 105967.
Online-Abstract

Chanyalew M, Abebe M, Endale B, Girma S, Tasew G, van Zandbergen G, Ritter U, Gadisa E, Aseffa A, Laskay T (2021): Enhanced production of pro-inflammatory cytokines and chemokines in Ethiopian cutaneous leishmaniasis upon exposure to Leishmania aethiopica.
Cytokine 145: 155289.
Online-Abstract

Charitidis FT, Adabi E, Thalheimer FB, Clarke C, Buchholz CJ (2021): Monitoring CAR T cell generation with a CD8-targeted lentiviral vector by single-cell transcriptomics.
Mol Ther Methods Clin Dev 23: 359-369.
Online-Abstract

Cheng TY, Lin YJ, Saburi W, Vieths S, Scheurer S, Schülke S, Toda M (2021): β-(1→4)-Mannobiose Acts as an Immunostimulatory Molecule in Murine Dendritic Cells by Binding the TLR4/MD-2 Complex.
Cells 10: 1774.
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Correia Pinheiro L, Giezen TJ, Wolff-Holz E, Weise M, Laslop A, Hidalgo-Simon A (2021): Identifiability of Biologicals: An Analysis Using EudraVigilance, the European Union's Database of Reports of Suspected Adverse Drug Reactions.
Clin Pharmacol Ther 110: 1311-1317.
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Costa J, Villa C, Verhoeckx K, Cirkovic-Velickovic T, Schrama D, Roncada P, Rodrigues PM, Piras C, Martín-Pedraza L, Monaci L, Molina E, Mazzucchelli G, Mafra I, Lupi R, Lozano-Ojalvo D, Larré C, Klueber J, Gelencser E, Bueno-Diaz C, Diaz-Perales A, Benedé S, Bavaro SL, Kuehn A, Hoffmann-Sommergruber K, Holzhauser T (2021): Are Physicochemical Properties Shaping the Allergenic Potency of Animal Allergens?.
Clin Rev Allergy Immunol 62: 1-36.
Online-Abstract

Datema MR, Lyons SA, Fernández-Rivas M, Ballmer-Weber B, Knulst AC, Asero R, Barreales L, Belohlavkova S, de Blay F, Clausen M, Dubakiene R, Fernández-Perez C, Fritsche P, Gislason D, Hoffmann-Sommergruber K, Jedrzejczak-Czechowicz M, Jongejan L, Kowalski ML, Kralimarkova TZ, Lidholm J, Papadopoulos NG, Popov TA, del Prado N, Purohit A, Reig I, Seneviratne SL, Sinaniotis A, Vassilopoulou E, Versteeg SA, Vieths S, Welsing PMJ, Mills ENC, Le TM, Zwinderman AH, van Ree R (2021): Estimating the Risk of Severe Peanut Allergy Using Clinical Background and IgE Sensitization Profiles.
Front Allergy 2: 670789.
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Davis CA, Haywood B, Vattipally S, Da Silva Filipe A, AlSaeed M, Smollet K, Baylis SA, Ijaz S, Tedder RS, Thomson EC, Abdelrahman TT (2021): Hepatitis E virus: Whole genome sequencing as a new tool for understanding HEV epidemiology and phenotypes.
J Clin Virol 139: 104738.
Online-Abstract

de Alwis R, Zellweger RM, Chua E, Wang LF, Chawla T, Sessions OM, Marlier D, Connolly JE, von Messling V, Anderson DE (2021): Systemic inflammation, innate immunity and pathogenesis after Zika virus infection in cynomolgus macaques are modulated by strain-specificity within the Asian lineage.
Emerg Microbes Infect 10: 1457-1470.
Online-Abstract

De Marchi L, Mainente F, Leonardi M, Scheurer S, Wangorsch A, Mahler V, Pilolli R, Sorio D, Zoccatelli G (2021): Allergenicity assessment of the edible cricket Acheta domesticus in terms of thermal and gastrointestinal processing and IgE cross-reactivity with shrimp.
Food Chem 359: 129878.
Online-Abstract

De Marchi L, Wangorsch A, Zoccatelli G (2021): Allergens from Edible Insects: Cross-reactivity and Effects of Processing.
Curr Allergy Asthma Rep 21: 35.
Online-Abstract

Dickel H, Kuehn A, Dickel B, Bauer A, Becker D, Fartasch M, Haeberle M, John SM, Mahler V, Skudlik C, Weisshaar E, Werfel T, Geier J, Diepgen TL (2021): Assessment of the effects of a work-related allergy to seafood on the reduction of earning capacity in the context of BK No. 5101.
Allergol Select 5: 33-44.
Online-Abstract

Droste A, Chaves G, Stein S, Trzmiel A, Schweizer M, Karl H, Musset B (2021): Zinc accelerates respiratory burst termination in human PMN.
Redox Biol 47: 102133.
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Eichler H, Feyer AK, Weitmann K, Hoffmann W, Henseler O, Opitz A, Patek A, Hans DN, Schönborn L, Greinacher A (2021): Population-Based Analysis of the Impact of Demographics on the Current and Future Blood Supply in the Saarland.
Transfus Med Hemother 48: 175-182.
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Englert L, Mahler V, Bonertz A (2021): Regulatory Requirements for the Quality of Allergen Products for Allergen Immunotherapy of Food Allergy.
Curr Allergy Asthma Rep 21: 32.
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Etna MP, Signorazzi A, Ricci D, Severa M, Rizzo F, Giacomini E, Gaggioli A, Bekeredjian-Ding I, Huckriede A, Coccia EM (2021): Human plasmacytoid dendritic cells at the crossroad of type I interferon-regulated B cell differentiation and antiviral response to tick-borne encephalitis virus.
PLoS Pathog 17: e1009505.
Online-Abstract

Fiack S, Koch-Gromus U, Kuhn J, Lübbing-Raukohl C (2021): Medizin und Medien - Symbiose oder Konflikt?.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 64: 1-2.
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Forkel S, Cevik N, Schill T, Worm M, Mahler V, Weisshaar E, Vieluf D, Pfützner W, Löffler H, Schön MP, Geier J, Buhl T (2021): Atopische Hautdiathese ist stärker mit spezifischen Kontaktallergien assoziiert als atopische Dermatitis.
J Dtsch Dermatol Ges 19: 231-240.
Online-Abstract

Fukuda S, Narendran S, Varshney A, Nagasaka Y, Wang SB, Ambati K, Apicella I, Pereira F, Fowler BJ, Yasuma T, Hirahara S, Yasuma R, Huang P, Yerramothu P, Makin RD, Wang M, Baker KL, Marion KM, Huang X, Baghdasaryan E, Ambati M, Ambati VL, Banerjee D, Bonilha VL, Tolstonog GV, Held U, Ogura Y, Terasaki H, Oshika T, Bhattarai D, Kim KB, Feldman SH, Aguirre JI, Hinton DR, Kerur N, Sadda SR, Schumann GG, Gelfand BD, Ambati J (2021): Alu complementary DNA is enriched in atrophic macular degeneration and triggers retinal pigmented epithelium toxicity via cytosolic innate immunity.
Sci Adv 7: eabj3658.
Online-Abstract

Fukuda S, Varshney A, Fowler BJ, Wang S, Narendran S, Ambati K, Yasuma T, Magagnoli J, Leung H, Hirahara S, Nagasaka Y, Yasuma R, Apicella I, Pereira F, Makin RD, Magner E, Liu X, Sun J, Wang M, Baker K, Marion KM, Huang X, Baghdasaryan E, Ambati M, Ambati VL, Pandey A, Pandya L, Cummings T, Banerjee D, Huang P, Yerramothu P, Tolstonog GV, Held U, Erwin JA, Paquola ACM, Herdy JR, Ogura Y, Terasaki H, Oshika T, Darwish S, Singh R, Mozaffari S, Bhattarai D, Kim KY, Hardin JW, Bennett CL, Hinton DR, Hanson TE, Röver C, Parang K, Kerur N, Liu J, Werner BC, Sutton SC, Sadda SR, Schumann GG, Gelfand BD, Gage FH, Ambati J (2021): Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration.
Proc Natl Acad Sci U S A 118: e2022751118.
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Glitscher M, Martín DH, Woytinek K, Schmidt B, Tabari D, Scholl C, Stingl JC, Seelow E, Choi M, Hildt E (2021): Targeting cholesterol metabolism as efficient antiviral strategy against the Hepatitis E virus.
Cell Mol Gastroenterol Hepatol 12: 159-180.
Online-Abstract

Glitscher M, Hildt E (2021): Hepatitis E virus egress and beyond - the manifold roles of the viral ORF3 protein.
Cell Microbiol 23: e13379.
Online-Abstract

Glitscher M, Hildt E (2021): Endosomal Cholesterol in Viral Infections - A Common Denominator?.
Front Physiol 12: 750544.
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Glitscher M, Himmelsbach K, Woytinek K, Schollmeier A, Johne R, Praefcke GJK, Hildt E (2021): Identification of the interferon-inducible GTPase GBP1 as major restriction factor for the Hepatitis E virus.
J Virol 95: e01564-20.
Online-Abstract

Gogesch P, Dudek S, van Zandbergen G, Waibler Z, Anzaghe M (2021): The Role of Fc Receptors on the Effectiveness of Therapeutic Monoclonal Antibodies.
Int J Mol Sci 22: 8947.
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Gonzalez-Klein Z, Cuevas-Zuviria B, Hernandez-Ramirez G, Wangorsch A, Pazos-Castro D, Romero-Sahagun A, Pacios LF, Tome-Amat J, Scheurer S, Diaz-Perales A, Garrido-Arandia M (2021): The key to the allergenicity of lipid transfer protein (LTP) ligands: A structural characterization.
Biochim Biophys Acta Mol Cell Biol Lipids 1866: 158928.
Online-Abstract

Goretzki A, Lin YJ, Schülke S (2021): Immune metabolism in allergies, does it matter? ‐ A review of immune metabolic basics and adaptations associated with the activation of innate immune cells in allergy.
Allergy 76: 3314-3331.
Online-Abstract

Greinacher A, Thiele T, Warkentin TE, Weisser K, Kyrle PA, Eichinger S (2021): Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination.
N Engl J Med 384: 2092-2101.
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Guerrouahen B, Elnaggar M, Al-Mohannadi A, Kizhakayil D, Bonini C, Benjamin R, Brentjens R, Buchholz CJ, Casorati G, Ferrone S, Locke FL, Martin F, Schambach A, Turtle C, Veys P, van der Vliet HJ, Maccalli C, EICCI Faculty Group (2021): Proceedings From the First International Workshop at Sidra Medicine: "Engineered Immune Cells in Cancer Immunotherapy (EICCI): From Discovery to Off-the-Shelf Development", 15 th-16 th February 2019, Doha, Qatar.
Front Immunol 11: 589381.
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Gürtler L, Seitz R, Schramm W (2021): Cerebral venous thrombosis after COVID-19 vaccination: is the risk of thrombosis increased by intravascular application of the vaccine?.
Infection 49: 1071–1074.
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Guth S, Hüser S, Roth A, Degen G, Diel P, Edlund K, Eisenbrand G, Engel KH, Epe B, Grune T, Heinz V, Henle T, Humpf HU, Jäger H, Joost HG, Kulling SE, Lampen A, Mally A, Marchan R, Marko D, Mühle E, Nitsche MA, Röhrdanz E, Stadler R, van Thriel C, Vieths S, Vogel RF, Wascher E, Watzl C, Nöthlings U, Hengstler JG (2021): Contribution to the ongoing discussion on fluoride toxicity.
Arch Toxicol 95: 2571-2587.
Online-Abstract

Hassan M, Krieg SC, Ndefo Nde C, Roos J, Maier TJ, El Rady EA, Raslan MA, Sadek KU, Manolikakes G (2021): Streamlined One-Pot Synthesis of Nitro Fatty Acids.
Eur JOC 2021: 2239-2252.
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Hein S, Benz NI, Eisert J, Herrlein ML, Oberle D, Dreher M, Stingl JC, Hildt C, Hildt E (2021): Comirnaty-Elicited and Convalescent Sera Recognize Different Spike Epitopes.
Vaccines (Basel) 9: 1419.
Online-Abstract

Heinzerling L, La Rosée P, Gutzmer R, Kramer R, Keller-Stanislawski B, Zierold S, Mentzer D (2021): Response to letter entitled: 'Re: Hematological immune related adverse events after treatment with immune checkpoint inhibitors.
Eur J Cancer 153: 272-273.

Hellmuth N, Brat C, Awad O, George S, Kahnt A, Bauer T, Huynh Phuoc HP, Steinhilber D, Angioni C, Hassan M, Hock KJ, Manolikakes G, Zacharowski K, Roos J, Maier TJ (2021): Structural Modifications Yield Novel Insights Into the Intriguing Pharmacodynamic Potential of Anti-inflammatory Nitro-Fatty Acids.
Front Pharmacol 12: 715076.
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Hennrich AA, Sawatsky B, Santos-Mandujano R, Banda DH, Oberhuber M, Schopf A, Pfaffinger V, Wittwer K, Riedel C, Pfaller CK, Conzelmann K (2021): Safe and effective two-in-one replicon-and-VLP minispike vaccine for COVID-19: Protection of mice after a single immunization.
PLoS Pathog 17: e1009064.
Online-Abstract

Henss L, Auste A, Schürmann C, Schmidt C, von Rhein C, Mühlebach MD, Schnierle BS (2021): The green tea catechin epigallocatechin gallate inhibits SARS-CoV-2 infection.
J Gen Virol 102: 001574.
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Herrmann M, Yampolsky LY (2021): False and true positives in arthropod thermal adaptation candidate gene lists.
Genetica 149: 143-153.
Online-Abstract

Hethey C, Hartung N, Wangorsch G, Weisser K, Huisinga W (2021): Physiology-based toxicokinetic modelling of aluminium in rat and man.
Arch Toxicol 95: 2977-3000.
Online-Abstract

Hörner M, Jerez-Longres C, Hudek A, Hook S, Yousefi OS, Schamel WWA, Hörner C, Zurbriggen MD, Ye H, Wagner HJ, Weber W (2021): Spatiotemporally confined red light-controlled gene delivery at single-cell resolution using adeno-associated viral vectors.
Sci Adv 7: eabf0797.
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Irving M, Lanitis E, Migliorini D, Ivics Z, Guedan S (2021): Choosing the Right Tool for Genetic Engineering: Clinical Lessons from Chimeric Antigen Receptor-T Cells.
Hum Gene Ther 32: 1044-1058.
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Ivics Z (2021): Potent CAR-T Cells Engineered With Sleeping Beauty Transposon Vectors Display a Central Memory Phenotype.
Gene Ther 28: 3-5.
Online-Abstract

Jacob T, Wangorsch A, Vogel L, Reuter A, Mahler V, Wöhrl BM (2021): A Novel Isoallergen Dau c 1.0401 in Carrot: Stability, Allergenicity, and Comparison with Other Isoallergens.
Mol Nutr Food Res 65: e2001110.
Online-Abstract

Janssen MP, Nuebling CM, Lery FX, Maryuningsih YS, Epstein JS (2021): A WHO tool for risk-based decision making on blood safety interventions.
Transfusion 61: 503-515.
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Jeong KY, Lee J, Yuk JE, Park JH, Ferreira F, Sang MK, Lee YS, Vogel L, Park KH, Park JW (2021): Characterization of the major allergen, Que ac 1, from sawtooth oak pollen.
Allergy 76: 2626-2629.
Online-Abstract

Jepsen K, Falk W, Brune F, Fimmers R, Jepsen S, Bekeredjian-Ding I (2021): Prevalence and antibiotic susceptibility trends of periodontal pathogens in the subgingival microbiota of German periodontitis patients: A retrospective surveillance study.
J Clin Periodontal 48: 1216-1227.
Online-Abstract

Johnen S, Harmening N, Marie C, Scherman D, Izsvák Z, Ivics Z, Walter P, Thumann G (2021): Electroporation-Based Genetic Modification of Primary Human Pigment Epithelial Cells using the Sleeping Beauty Transposon System.
J Vis Exp: e61987.
Online-Abstract

Kaiser LM, Harms M, Sauter D, Rawat VPS, Glitscher M, Hildt E, Tews D, Hunter Z, Münch J, Buske C (2021): Targeting of CXCR4 by the Naturally Occurring CXCR4 Antagonist EPI-X4 in Waldenström’s Macroglobulinemia.
Cancers (Basel) 13: 826.
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Kamp C, Becker B, Matheis W, Öppling V, Bekeredjian-Ding I (2021): How to draw the line - Raman spectroscopy as a tool for the assessment of biomedicines.
Biol Chem 402: 1001-1006.
Online-Abstract

Keipert C, Drechsel-Bäuerle U, Oberle D, Müller-Olling M, Hilger A (2021): Epidemiological Challenges in Rare Bleeding Disorders: FVIII Inhibitor Incidence in Haemophilia A Patients - A Known Issue of Unknown Origin.
Int J Environ Res Public Health 18: 225.
Online-Abstract

Klimka A, Mertins S, Nicolai AK, Rummler LM, Higgins PG, Günther SD, Tosetti B, Krut O, Krönke M (2021): Epitope-specific immunity against Staphylococcus aureus coproporphyrinogen III oxidase.
NPJ Vaccines 6: 11.
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König R, Münk C (2021): Special Issue: 'Innate Immune Sensing of Viruses and Viral Evasion'.
Viruses 13: 567.
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Konkle BA, Recht M, Hilger A, Marks P (2021): The critical need for postmarketing surveillance in gene therapy for haemophilia.
Haemophilia 27: 126-131.
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Krause M, Crauwels P, Blanco Pérez F, Globisch M, Wangorsch A, Henle T, Lidholm J, van Zandbergen G, Vieths S, Scheurer S, Toda M (2021): Human monocyte-derived type 1 and 2 macrophages recognize Ara h 1, a major peanut allergen, by different mechanisms.
Sci Rep 11: 10141.
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Kurki P, Barry S, Bourges I, Tsantili P, Wolff-Holz E (2021): Safety, Immunogenicity and Interchangeability of Biosimilar Monoclonal Antibodies and Fusion Proteins: A Regulatory Perspective.
Drugs 81: 1881-1896.
Online-Abstract

Lapaillerie D, Lelandais B, Mauro E, Lagadec F, Tumiotto C, Miskey C, Ferran G, Kuschner N, Calmels C, Métifiot M, Rooryck C, Ivics Z, Ruff M, Zimmer C, Lesbats P, Toutain J, Parissi V (2021): Modulation of the intrinsic chromatin binding property of HIV-1 integrase by LEDGF/p75.
Nucleic Acids Res 49: 11241-11256.
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Lasch F, Guizzaro L, Aguirre Dávila L, Müller-Vahl K, Koch A (2021): Potential impact of COVID-19 on ongoing clinical trials: a simulation study with the neurological Yale Global Tic Severity Scale based on the CANNA-TICS study.
Pharm Stat 20: 675-691.
Online-Abstract

Lin YJ, Flaczyk A, Wolfheimer S, Goretzki A, Jamin A, Wangorsch A, Vieths S, Scheurer S, Schülke S (2021): The Fusion Protein rFlaA:Betv1 Modulates DC Responses by a p38-MAPK and COX2-Dependent Secretion of PGE2 from Epithelial Cells.
Cells 10: 3415.
Online-Abstract

Lin YJ, Papp G, Miskey C, Fiedler A, Goretzki S, Wolfheimer S, Crauwels P, Ivics Z, van Zandbergen G, Vieths S, Scheurer S, Schülke S (2021): The flagellin:allergen fusion protein rFlaA:Betv1 induces a MyD88- and MAPK-dependent activation of glucose metabolism in macrophages.
Cells 10: 2614.
Online-Abstract

Lyons SA, Datema MR, Le TTM, Asero R, Barreales L, Belohlavkova S, de Blay F, Clausen M, Dubakiene R, Fernández-Perez C, Fritsche P, Gislason D, Hoffmann-Sommergruber K, Jedrzejczak-Czechowicz M, Longejan L, Kowalski ML, Kralimarkova T, Lidholm J, Papdopoulos NG, Bontoppidan B, Popov TA, Del Prado N, Purohit A, Reig I, Seneviratne SL, Sinaniotis A, Vassilopoulou E, Versteeg SA, Vieths S, Zwinderman AH, Welsing PMJ, Mills ENC, Ballmer-Weber B, Knulst AC, Fernández-Rivas M, Van Ree R (2021): Walnut Allergy across Europe: Distribution of Allergen Sensitization Patterns and Prediction of Severity.
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Mahler V (2021): Neue Allergene für die Berufsdermatologie?.
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