Paul-Ehrlich-Institut

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Publications in 2022

Please note: Authors from the Paul-Ehrlich-Institut are highlighted in bold. For online abstracts or full text publications, please follow the links.

Aghilipour H, Fiedler S, Funk MB (2022): Zuständigkeiten des Paul-Ehrlich-Instituts auf der Basis der neuen EU-Verordnung für In-vitro-Diagnostika.
Bulletin zur Arzneimittelsicherheit 13: 9-15.
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Albrecht M, Halle O, Gaedcke S, Pallenberg ST, Camargo Neumann J, Witt M, Roediger J, Schumacher M, Jirmo AC, Warnecke G, Jonigk D, Braubach P, DeLuca D, Hansen G, Dittrich AM (2022): Interleukin-17A and interleukin-22 production by conventional and non-conventional lymphocytes in three different end-stage lung diseases.
Clin Transl Immunology 11: e1398.
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Albrecht M, Schaub B, Gilles S, Köhl J, Altrichter S, Voehringer D, Spillner E, Ehlers M, Jönsson F, Loser K, Mayer JU, Rösner LM, Möbs C, Heine G, Pfützner W (2022): Current research and unmet needs in allergy and immunology in Germany: report presented by the DGfI and DGAKI task force Allergy & Immunology.
Eur J Immunol 52: 851-855.
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Alirezaeizanjani Z, Trösemeier JH, Kamp C, Rudorf S (2022): Tailoring Codon Usage to the Underlying Biology for Protein Expression Optimization.
Methods Mol Biol 2406: 85-92.
Online-Abstract

Anliker B, Childs L, Rau J, Renner M, Schüle S, Schuessler-Lenz M, Sebe A (2022): Regulatory Considerations for Clinical Trial Applications with CRISPR-Based Medicinal Products.
CRISPR J 5: 364-376.
Online-Abstract

Arrazuria R, Kerscher B, Huber KE, Hoover JL, Lundberg CV, Hansen JU, Sordello S, Renard S, Aranzana-Climent V, Hughes D, Gribbon P, Friberg LE, Bekeredjian-Ding I (2022): Expert workshop summary: Advancing toward a standardized murine model to evaluate treatments for antimicrobial resistance lung infections.
Front Microbiol 13: 988725.
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Arrazuria R, Kerscher B, Huber KE, Hoover JL, Lundberg CV, Hansen JU, Sordello S, Renard S, Aranzana-Climent V, Hughes D, Gribbon P, Friberg LE, Bekeredjian-Ding I (2022): Variability of murine bacterial pneumonia models used to evaluate antimicrobial agents.
Front Microbiol 13: 988728.
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Arroyo M, Hastert FD, Zhadan A, Schelter F, Zimbelmann S, Rausch C, Ludwig AK, Carell T, Cardoso MC (2022): Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidation.
Nat Commun 13: 5173.
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Artunc F, Bohnert BN, Schneider JC, Staudner T, Sure F, Ilyaskin AV, Wörn M, Essigke D, Janessa A, Nielsen NV, Birkenfeld AL, Etscheid M, Haerteis S, Korbmacher C, Kanse SM (2022): Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice.
Pflugers Arch 474: 217-229.
Online-Abstract

Atemnkeng J, Heinrich J, Samukange WT, Kafere C, Mbunkah HA, Schoner C, Reinhardt J (2022): Report on the GHPP-BloodTrain online workshop on "Authorisation and Licensing of Blood Establishments - Review of quality documentation of blood and blood components", 5th-8th of July 2021.
Biologicals 80: 1-5.
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Auste A, Mühlebach MD (2022): Concentrating all helper protein functions on a single entity allows rescue of recombinant measles virus by transfection of just two plasmids.
J Gen Virol 103: 001815.
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Baylis SA, Adlhoch C, Childs L, and the HEV Sequencing Study Group (2022): An Evaluation of Hepatitis E Virus Molecular Typing Methods.
Clin Chem 68: 181-191.
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Baylis SA, Nübling CM (2022): Nucleic Acid Testing of Viral Pathogens: Traceability of the International Unit.
Clin Chem 68: 257-258.
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Baylis SA, O'Flaherty N, Burke L, Hogema B, Corman VM (2022): Identification of rabbit hepatitis E virus (HEV) and novel HEV clade in Irish blood donors.
J Hepatol 77: 870-872.
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Behr-Gross ME, Regourd E, Holtkamp W (2022): Collaborative study for the establishment of Ph. Eur. Human immunoglobulin for electrophoresis BRP batch 4.
Pharmeur Bio Sci Notes 2022: 37-54.
Online-Abstract

Bender D, Glitscher M, Hildt E (2022): Die Virushepatitiden A bis E: Prävalenz, Erregermerkmale und Pathogenese.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 65: 139-148.
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Bender D, Hildt E (2022): Back to the Roots: Noncanonical Retrograde Trafficking of the HBV Nucleocapsids.
Cell Mol Gastroenterol Hepatol 15: 797-798.
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Berg P, Schönefeld S, Ruppert-Seipp G, Funk MB (2022): Regulatory Measures to Improve the Safety of CAR-T-Cell Treatment.
Transfus Med Hemother 50: 218-225.
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Berge-Seidl S, Nielsen NV, Rodriguez Alfonso AA, Etscheid M, Kandanur SPS, Haug BE, Stensland M, Thiede B, Karacan M, Preising N, Wiese S, Ständker L, Declerck PJ, Løset GÅ, Kanse SM (2022): Identification of a Phage Display-Derived Peptide Interacting with the N-Terminal Region of Factor VII Activating Protease (FSAP) Enables Characterization of Zymogen Activation.
ACS Chem Biol 17: 2631-2642.
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Bergner S, Grüger T, Huber M, Lütkehermölle W, Paeschke N, Palissa H, Stephan K, Cibura S, Keller-Stanislawski B (2022): Instrumente behördlicher Kommunikation zu Anwendungsrisiken von Arzneimitteln.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 65: 567-576.
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Bernard MC, Waldock J, Commandeur S, Strauß L, Trombetta CM, Marchi S, Zhou F, van de WItte S, van Amsterdam P, Ho S, Hoschler K, Lugovtsev V, Weir JP, Montomoli E, Cox RJ, Engelhardt OG, Friel D, Wagner R, Ollinger T, Germain S, Sediri-Schön H (2022): Validation of a Harmonized Enzyme-Linked-Lectin-Assay (ELLA-NI) Based Neuraminidase Inhibition Assay Standard Operating Procedure (SOP) for Quantification of N1 Influenza Antibodies and the Use of a Calibrator to Improve the Reproducibility of the ELLA-NI With Reverse Genetics Viral and Recombinant Neuraminidase Antigens: A FLUCOP Collaborative Study.
Front Immunol 13: 909297.
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Bexte T, Botezatu L, Miskey C, Reindl LM, Campe J, Mertlitz S, Gebel V, Schubert R, Cremer A, Rettinger E, Prommersberger S, Penack O, Wels WS, Hudecek M, Ivics Z, Ullrich E (2022): High antileukemic efficiency of CD19-CAR NK cells engineered with Sleeping Beauty transposon vectors.
Klin Padiatr 234: 190-191.
Online-Abstract

Blanco-Pérez F, Gonzalez-Menendez I, Stassen M, Kato Y, Laiño J, Kirberg J, Krause M, Martella M, Shibata N, Quintanilla-Martinez L, Feyerabend TB, Rodewald HR, Galli SJ, Vieths S, Scheurer S, Toda M (2022): Mast cells partly contribute to allergic enteritis development: findings in two different mast cell-deficient mice.
Allergy 77: 1051-1054.
Online-Abstract

Bold CS, Baltissen D, Ludewig S, Back MK, Just J, Kilian L, Erdinger S, Banicevic M, Rehra L, Almouhanna F, Nigri M, Wolfer DP, Spilger R, Rohr K, Kann O, Buchholz CJ, von Engelhardt J, Korte M, Müller UC (2022): APPsα Rescues Tau-Induced Synaptic Pathology.
J Neurosci 42: 5782-5802.
Online-Abstract

Bonertz A, Tripathi A, Zimmer J, Reeb C, Kaul S, Bridgewater J, Rabin RL, SI JE, Vieths S (2022): A regulator’s view on AIT clinical trials in the United States and Europe: Why successful studies fail to support licensure.
J Allergy Clin Immunol 149: 812-818.
Online-Abstract

Breitenbach T, Englert N, Osmanoglu Ö, Rukoyatkina N, Wangorsch G, Heinze K, Friebe A, Butt E, Feil R, Dittrich M, Gambaryan S, Dandekar T (2022): A modular systems biological modelling framework studies cyclic nucleotide signaling in platelets.
J Theor Biol 550: 111222.
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Chapman MD, Custovic A, Mills CEN, Holzhauser T: Molecular exposure: Systematic approaches, clinical significance, and harmonisation.
In: Hoffmann-Sommergruber K, Hilger C, Santos A, de las Vecillas L, Dramburg S / EAACI (Hrsg.), Molecular Allergology User’s Guide 2.0: John Wiley & Sons Ltd., 2022. S. 157-170, ISBN 978-3-9524815-4-7

Costa J, Bavaro SL, Benedé S, Diaz-Perales A, Bueno-Diaz C, Gelencser E, Klueber J, Larré C, Lozano-Ojalvo D, Lupi R, Mafra I, Mazzuchelli G, Molina E, Monaci L, Martin-Petraza L, Piras C, Rodrigues PM, Roncada P, Schrama D, Cirkovic-Velickovic T, Verhoeckx K, Villa C, Kuehn A, Hoffmann-Sommergruber K, Holzhauser T (2022): Are Physicochemical Properties Shaping the Allergenic Potency of Plant Allergens?.
Clin Rev Allergy Immunol 62: 37-63.
Online-Abstract

Demircan MB, Mgbecheta PC, Kresinsky A, Schnoeder TM, Schröder K, Heidel FH, Böhmer FD (2022): Combined Activity of the Redox-Modulating Compound Setanaxib (GKT137831) with Cytotoxic Agents in the Killing of Acute Myeloid Leukemia Cells.
Antioxidants (Basel) 11: 513.
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Demircan MB, Schnoeder TM, Mgbecheta PC, Schröder K, Böhmer FD, Heidel FH (2022): Context-specific effects of NOX4 inactivation in acute myeloid leukemia (AML).
J Cancer Res Clin Oncol 148: 1983–1990.
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Denk D, Petrocelli V, Conche C, Drachsler M, Ziegler PK, Braun A, Kress A, Nicolas AM, Mohs K, Becker C, Neurath MF, Farin HF, Buchholz CJ, Andreux PA, Rinsch C, Greten FR (2022): Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy.
Immunity 55: 2059-2073.
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Dickel H, Bauer A, Brehler R, Mahler V, Merk HF, Neustädter I, Strömer K, Werfel T, Worm M, Geier J (2022): S1-Leitlinie Kontaktekzem.
J Dtsch Dermatol Ges 20: 711-734.
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Ding L, Li J, Li X, Qu B (2022): Evolutionary and Mutational Characterization of the First H5N8 Subtype Influenza A Virus in Humans.
Pathogens 11: 666.
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Donnadieu E, Luu M, Alb M, Anliker B, Arcangeli S, Bonini C, De Angelis B, Choudhary R, Espie D, Galy A, Holland C, Ivics Z, Kantari-Mimoun C, Kersten MJ, Köhl U, Kuhn C, Laugel B, Locatelli F, Marchiq I, Markman J, Moresco MA, Morris E, Negre H, Quintarelli C, Rade M, Reiche K, Renner M, Ruggerio E, Sanges C, Stauss H, Themeli M, Van den Brulle J, Hudecek M, Casucci M (2022): Time to evolve: predicting engineered T cell-associated toxicity with next-generation models.
J Immunother Cancer 10: e003486.
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Ebenig A, Lange MV, Mühlebach MD (2022): Versatility of live-attenuated measles viruses as platform technology for recombinant vaccines.
NPJ Vaccines 7: 119.
Online-Abstract

Ebenig A, Muraleedharan S, Kazmierski J, Todt D, Auste A, Anzaghe M, Gömer A, Postmus D, Gogesch P, Niles M, Plesker R, Miskey C, Gellhorn Serra M, Breithaupt A, Hörner C, Kruip C, Ehmann R, Ivics Z, Waibler Z, Pfaender S, Wyler E, Landthaler M, Kupke A, Nouailles G, Goffinet C, Brown RJP, Mühlebach MD (2022): Vaccine-associated enhanced respiratory pathology in COVID-19 hamsters after TH2-biased immunization.
Cell Rep 40: 111214.
Online-Abstract

Eisenbrand G, Baum M, Cartus AT, Diel P, Engel KH, Engeli B, Epe B, Grune T, Guth S, Haller D, Heinz V, Hellwig M, Hengstler JG, Henle T, Humpf HU, Jäger H, Joost HG, Kulling S, Lachenmeier DW, Lampen A, Leist M, Mally A, Marko D, Nöthlings U, Röhrdanz E, Roth A, Spranger J, Stadler R, Vieths S, Wätjen W, Steinberg P (2022): Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds-a hypothesis.
Arch Toxicol 96: 1905-1914.
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Etscheid M, Hanschmann KM, Sandset PM, Kanse SM (2022): Development of a Factor VII Activating Protease (FSAP) generation assay and its application in studying FSAP in venous thrombosis.
Thromb Res 220: 24-34.
Online-Abstract

Fekadu J, Modlich U, Bader P, Bakhtiar S (2022): Understanding the Role of LFA-1 in Leukocyte Adhesion Deficiency Type I (LAD I): Moving towards Inflammation?.
Int J Mol Sci 23: 3578.
Online-Abstract

Fischer N, Gulich B, Tönjes RR, Godehardt AW (2022): Limited environmental stability of infectious porcine endogenous retrovirus type C; Usage of reverse transcriptase in combination with viral RNA as markers for infectious virus.
Xenotransplantation 29: e12738.
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Gasparics Á, Sebe A (2022): Forward Genetic Screens as Tools to Investigate Role and Mechanisms of EMT in Cancer.
Cancers (Basel) 14: 5928.
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Geier J, Ballmer-Weber B, Buhl T, Rieker-Schwienbacher J, Mahler V, Dickel H, Schubert S, IVDK (2022): Is benzyl alcohol a significant contact sensitizer?.
J Eur Acad Dermatol Venereol 36: 866-872.
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Glitscher M, Hildt E, Bender D (2022): Hepatitis B und C: Mechanismen der virusinduzierten Leberpathogenese und Tumorentstehung.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 65: 228-237.
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Gömer A, Brown RJP, Pfaender S, Deterding K, Reuter G, Orton R, Seitz S, Bock CT, Cavalleri JMV, Pietschmann T, Wedemeyer H, Steinmann E, Todt D (2022): Intra-host analysis of hepaciviral glycoprotein evolution reveals signatures associated with viral persistence and clearance.
Virus Evol 8: veac007.
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Görgülü E, Gu W, Trebicka J, Mücke VT, Mücke MM, Friedrich-Rust M, Bojunga J, Zeuzem S, Finkelmeier F, Peiffer KH (2022): Acute-on-chronic liver failure (ACLF) precipitated by severe alcoholic hepatitis: another collateral damage of the COVID-19 pandemic?.
Gut 71: 1036-1038.
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Goretzki A, Lin YJ, Zimmermann J, Rainer H, Junker AC, Wolfheimer S, Vieths S, Scheurer S, Schülke S (2022): Role of Glycolysis and Fatty Acid Synthesis in the Activation and T Cell-Modulating Potential of Dendritic Cells Stimulated with a TLR5-Ligand Allergen Fusion Protein.
Int J Mol Sci 23: 12695.
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Goretzki A, Zimmermann J, Lin YJ, Schülke S (2022): Immune Metabolism-An Opportunity to Better Understand Allergic Pathology and Improve Treatment of Allergic Diseases?.
Front Allergy 3: 825931.
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Gramstad OR, Kandanur SPS, Etscheid M, Nielsen EW, Kanse SM (2022): Factor VII activating protease (FSAP) is not essential in the pathophysiology of angioedema in patients with C1 inhibitor deficiency.
Mol Immunol 142: 95-104.
Online-Abstract

Guedan S, Luu M, Ammar D, Barbao P, Bonini C, Bousso P, Buchholz CJ, Casucci M, De Angelis B, Donnadieu E, Espie D, Greco B, Groen R, Huppa JB, Kantari-Mimoun C, Laugel B, Mantock M, Markman JL, Morris E, Quintarelli C, Rade M, Reiche K, Rodriguez-Garcia A, Rodriguez-Madoz JR, Ruggiero E, Themeli M, Hudecek M, Marchiq I (2022): Time 2EVOLVE: predicting efficacy of engineered T-cells – how far is the bench from the bedside?.
J Immunother Cancer 10: e003487.
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Guimaraes Koch SS, Thorpe R, Kawasaki N, Lefranc MP, Malan S, Martin ACR, Mignot G, Plückthun A, Rizzi M, Shubat S, Weisser K, Balocco R (2022): International nonproprietary names for monoclonal antibodies: an evolving nomenclature system.
MAbs 14: 2075078.
Online-Abstract

Hastert FD, Hein S, von Rhein C, Benz NI, Husria Y, Oberle D, Maier TJ, Hildt E, Schnierle BS (2022): The SARS-CoV-2 Variant Omicron Is Able to Escape Vaccine-Induced Humoral Immune Responses, but Is Counteracted by Booster Vaccination.
Vaccines (Basel) 10: 794.
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Hastert FD, Henss L, von Rhein C, Gerbeth J, Wieters I, Borgans F, Khodamoradi Y, Zacharowski K, Rohde G, Vehreschild MJGT, Schnierle B (2022): Longitudinal Analysis of Coronavirus-Neutralizing Activity in COVID-19 Patients.
Viruses 14: 882.
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Hauptstein N, Dirauf M, Wittwer K, Cinar G, Siering O, Raschig M, Lühmann T, Scherf-Clavel O, Sawatsky B, Nischang I, Schubert US, Pfaller CK, Meinel L (2022): PEtOxylated Interferon-α2a Bioconjugates Addressing H1N1 Influenza A Virus Infection.
Biomacromolecules 23: 3593-3601.
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Hauptstein N, Pouyan P, Wittwer K, Cinar G, Scherf-Clavel O, Raschig M, Licha K, Lühmann T, Nischang I, Schubert US, Pfaller CK, Haag R, Meinel L (2022): Polymer selection impacts the pharmaceutical profile of site-specifically conjugated Interferon-α2a.
J Control Release 348: 881-892.
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Heim C, Moser LM, Merker M, Wels WS, Ivics Z, Bönig H, Ullrich E, Klusmann JH, Bader P, Rettinger E (2022): ErbB2-CAR mediated immunotherapy for the treatment of high-risk rhabdomyosarcoma.
Klin Padiatr 234: 190.
Online-Abstract

Hein S, Herrlein ML, Mhedhbi I, Bender D, Haberger V, Benz N, Eisert J, Stingl J, Dreher M, Oberle D, Schulze J, Mache C, Budt M, Hildt C, Wolff T, Hildt E (2022): Analysis of BNT162b2- and CVnCoV-elicited sera and of convalescent sera towards SARS-CoV-2 viruses.
Allergy 77: 2080–2089.
Online-Abstract

Hein S, Mhedhbi I, Zahn T, Sabino C, Benz NI, Husria Y, Renelt PM, Braun F, Oberle D, Maier TJ, Hildt C, Hildt E (2022): Quantitative and Qualitative Difference in Antibody Response against Omicron and Ancestral SARS‐CoV‐2 after Third and Fourth Vaccination.
Vaccines (Basel) 10: 796.
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Herrlein ML, Hein S, Zahn T, Mhedhbi I, Raupach J, Husria Y, Benz NI, Eisert J, Bender D, Haberger V, Hastert FD, Henss L, Schnierle BS, Stingl JC, Dreher M, Hildt E (2022): Comparative Investigation of Methods for Analysis of SARS-CoV-2-Spike-Specific Antisera.
Viruses 14: 410.
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Herrlein ML, Schmanke P, Elgner F, Sabino C, Akhras S, Bender D, Glitscher M, Tabari D, Scholl C, Stingl J, Hildt E (2022): Catch Me if You Can: the Crosstalk of Zika Virus and the Restriction Factor Tetherin.
J Virol 96: e0211721.
Online-Abstract

Hildt E (2022): Virale Hepatitis – ein versteckter Killer.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 65: 137-138.
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Hildt E (2022): Übersicht über die in der EU zugelassenen COVID-19-Impfstoffe – von der Technologie über die klinische Prüfung zur Zulassung.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 65: 1237–1243.
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Hildt E, Schaade L (2022): Impfungen als Instrument der Pandemiebewältigung.
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 65: 1235-1236.
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Ho N, Agarwal S, Milani M, Cantore A, Buchholz CJ, Thalheimer FB (2022): In vivo generation of CAR T cells in the presence of human myeloid cells.
Mol Ther Methods Clin Dev 26: 144-156.
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Huber S, Braun NJ, Schmacke LC, Quek JP, Murra R, Bender D, Hildt E, Luo D, Heine A, Steinmetzer T (2022): Structure-Based Optimization and Characterization of Macrocyclic Zika Virus NS2B-NS3 Protease Inhibitors.
J Med Chem 65: 6555-6572.
Online-Abstract

Jepsen K, Falk W, Brune F, Cosgarea R, Fimmers R, Bekeredjian-Ding I, Jepsen S (2022): Prevalence and Antibiotic Susceptibility Trends of Selected Enterobacteriaceae, Enterococci, and Candida albicans in the Subgingival Microbiota of German Periodontitis Patients: A Retrospective Surveillance Study.
Antibiotics (Basel) 11: 385.
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Jia W, Asare E, Liu T, Zhang P, Wang Y, Wang s, Shen D, Miskey C, Gao B, Ivics Z, Qian Q, Song C (2022): Horizontal Transfer and Evolutionary Profiles of Two Tc1/ DD34E Transposons ( ZB and SB) in Vertebrates.
Genes (Basel) 13: 2239.
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Jutel M, Torres MJ, Palomares O, Akdis CA, Eiwegger T, Untersmayr E, Barber D, Zemelka-Wiacek M, Kosowska A, Palmer E, Vieths S, Mahler V, Canonica GW, Nadeau K, Shamji MH, Agache I, EAACI Research and Outreach Committee Group (2022): COVID-19 vaccination in patients receiving allergen immunotherapy (AIT) or biologicals - EAACI recommendations.
Allergy 77: 2313-2336.
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Kahnt AS, Angioni C, Göbel T, Hofmann B, Roos J, Steinbrink SD, Rörsch F, Thomas D, Geisslinger G, Zacharowski K, Grösch S, Steinhilber D, Maier TJ (2022): Inhibitors of Human 5-Lipoxygenase Potently Interfere With Prostaglandin Transport.
Front Pharmacol 12: 782584.
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Kehr S, Berg P, Müller S, Fiedler SA, Meyer B, Ruppert-Seipp G, Witzenhausen C, Wolf ME, Henkes HH, Oberle D, Keller-Stanislawski B, Funk MB (2022): Long-term outcome of patients with vaccine-induced immune thrombotic thrombocytopenia and cerebral venous sinus thrombosis.
NPJ Vaccines 7: 76.
Online-Abstract

Khaleva E, Rattu A, Brightling C, Bush A, Bossios A, Bourdin A, Chung KF, Chaudhuri R, Coleman C, Dahlén SE, Djukanovic R, Deschildre A, Fleming L, Fowler SJ, Gupta A, Hamelmann E, Hashimoto S, Hedlin G, Koppelman GH, Melén E, Murray CS, Pilette C, Porsbjerg C, Pike KC, Rusconi F, Williams C, Ahrens B, Alter P, Anckers F, van den Berge M, Blumchen K, Brusselle G, Clarke GW, Cunoosamy D, Dahlén B, Dixey P, Exley A, Frey U, Gaillard EA, Giovannini-Chami L, Grigg J, Hartenstein D, Heaney LG, Karadag B, Kaul S, Kull I, Licari A, Maitland-van der Zee AH, Mahler V, Schoos AM, Nagakumar P, Negus J, Nielsen H, Paton J, Pijnenburg M, Ramiconi V, Vilarnau SR, Principe S, Rutjes N, Saglani S, Seddon P, Singer F, Staudinger H, Turner S, Vijverberg S, Winders T, Yasinska V, Roberts G, COMSA working group in the 3TR consortium (2022): Development of Core Outcome Measures sets for paediatric and adult Severe Asthma (COMSA).
Eur Respir J 61: 2200606.
Online-Abstract

Kim YJ, Manna D, Etscheid M, Leergaard TB, Kanse SM (2022): Factor VII activating protease (FSAP) inhibits the outcome of ischemic stroke in mouse models.
FASEB J 36: e22564.
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Knezevic I, Mattiuzzo G, Page M, Nuebling CM, Griffiths E, Minor P (2022): Complexity of serological assays and misunderstandings of WHO International Units.
Clin Chem Lab Med 60: e223-e224.
Online-Abstract

Knezevic I, Mattiuzzo G, Page M, Minor P, Griffiths E, Nübling CM, Moorthy V (2022): WHO International Standard for evaluation of the antibody response to COVID-19 vaccines: call for urgent action by the scientific community.
Lancet Microbe 3: e235-e240.
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Krauter S, Buescher N, Bräuchle E, Ortega Iannazzo S, Penner I, Krämer N, Gogesch P, Thomas S, Kreutz M, Dejung M, Freiwald A, Butter F, Waibler Z, Plachter B (2022): An Attenuated Strain of Human Cytomegalovirus for the Establishment of a Subviral Particle Vaccine.
Vaccines (Basel) 10: 1326.
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Krijnse Locker J (2022): Tips and tricks of viruses; unconventional egress.
Mol Microbiol 117: 1291-1292.
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Kropp M, Harmening N, Bascuas T, Johnen S, De Clerck E, Fernández V, Ronchetti M, Cadossi R, Zanini C, Scherman D, Ivics Z, Marie C, Izsvák Z, Thumann G (2022): GMP-Grade Manufacturing and Quality Control of a Non-Virally Engineered Advanced Therapy Medicinal Product for Personalized Treatment of Age-Related Macular Degeneration.
Biomedicines 10: 2777.
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Kurki P, Kang HN, Ekman N, Knezevic I, Weise M, Wolff-Holz E (2022): Regulatory Evaluation of Biosimilars: Refinement of Principles Based on the Scientific Evidence and Clinical Experience.
BioDrugs 36: 359-371.
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Liu M, Zhou T, Sheets R, Meyer H, Knezevic I (2022): WHO informal consultation on regulatory considerations for evaluation of the quality, safety and efficacy of RNA-based prophylactic vaccines for infectious diseases, 20-22 April 2021.
Emerg Microbes Infect 11: 384-391.
Online-Abstract

Lohse S, Sternjakob-Marthaler A, Lagemann P, Schöpe J, Rissland J, Seiwert N, Pfuhl T, Müllendorff A, Kiefer LS, Vogelgesang M, Vella L, Denk K, Vicari J, Zwick A, Lang I, Weber G, Geisel J, Rech J, Schnabel B, Hauptmann G, Holleczek B, Scheiblauer H, Wagenpfeil S, Smola S (2022): German federal-state-wide seroprevalence study of 1st SARS-CoV-2 pandemic wave shows importance of long-term antibody test performance.
Commun Med (Lond) 2: 52.
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Mahler V, Junker AC (2022): Anaphylaxie auf Zusatzstoffe in Impfstoffen.
Allergo J 31: 22-39.
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Mahler V, Junker AC (2022): Anaphylaxis to additives in vaccines.
Allergo J Int 31: 123-136.
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Marx C, Sonnemann J, Maddocks ODK, Marx-Blümel L, Beyer M, Hoelzer D, Thierbach R, Maletzki C, Linnebacher M, Heinzel T, Krämer OH (2022): Global metabolic alterations in colorectal cancer cells during irinotecan-induced DNA replication stress.
Cancer Metab 10: 10.
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