Paul-Ehrlich-Institut

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Publications Dr. Christian Pfaller

Please note: Authors from the Paul-Ehrlich-Institut are highlighted in bold. For online abstracts or full text publications, please follow the links.

Hauptstein N, Dirauf M, Wittwer K, Cinar G, Siering O, Raschig M, Lühmann T, Scherf-Clavel O, Sawatsky B, Nischang I, Schubert US, Pfaller CK, Meinel L (2022): PEtOxylated Interferon-α2a Bioconjugates Addressing H1N1 Influenza A Virus Infection.
Biomacromolecules 23: 3593-3601.
Text

Hauptstein N, Pouyan P, Wittwer K, Cinar G, Scherf-Clavel O, Raschig M, Licha K, Lühmann T, Nischang I, Schubert US, Pfaller CK, Haag R, Meinel L (2022): Polymer selection impacts the pharmaceutical profile of site-specifically conjugated Interferon-α2a.
J Control Release 348: 881-892.
Text

Shin DL, Chludzinski E, Wu NH, Peng JY, Ciurkiewicz M, Sawatsky B, Pfaller CK, Baechlein C, von Messling V, Haas L, Beineke A, Herrler G (2022): Overcoming the Barrier of the Respiratory Epithelium during Canine Distemper Virus Infection.
mBio 13: e0304321.
Online-Abstract

Siering O, Cattaneo R, Pfaller CK (2022): C Proteins: Controllers of Orderly Paramyxovirus Replication and of the Innate Immune Response.
Viruses 14: 137.
Online-Abstract

Hennrich AA, Sawatsky B, Santos-Mandujano R, Banda DH, Oberhuber M, Schopf A, Pfaffinger V, Wittwer K, Riedel C, Pfaller CK, Conzelmann K (2021): Safe and effective two-in-one replicon-and-VLP minispike vaccine for COVID-19: Protection of mice after a single immunization.
PLoS Pathog 17: e1009064.
Online-Abstract

Pfaller CK, George CX, Samuel CE (2021): Adenosine Deaminases Acting on RNA (ADARs) and Viral Infections.
Annu Rev Virol 8: 239-264.
Online-Abstract

Siering O, Sawatsky B, Pfaller CK (2021): C Protein is Essential for Canine Distemper Virus Virulence and Pathogenicity in Ferrets.
J Virol 95: e01840-20.
Online-Abstract

Wittwer K, Anderson DE, Pfeffermann K, Cox RM, Wolf JD, Santibanez S, Mankertz A, Plesker R, Sticher ZM, Kolkykhalov AA, Natchus MG, Pfaller CK, Plemper RK, von Messling V (2021): Small-molecule polymerase inhibitor protects non-human primates from measles and reduces shedding.
Nat Commun 12: 5233.
Text

Ayasoufi K, Pfaller CK (2020): Seek and hide: the manipulating interplay of measles virus with the innate immune system.
Curr Opin Virol 41: 18-30.
Online-Abstract

Ayasoufi K, Pfaller CK, Evgin L, Khadka RH, Tritz ZP, Goddery EN, Fain CE, Yokanovich LT, Himes BT, Jin F, Zheng J, Schuelke MR, Hansen MJ, Tung W, Parney IF, Pease LR, Vile RG, Johnson AJ (2020): Brain cancer induces systemic immunosuppression through release of non-steroid soluble mediators.
Brain 143: 3629-3652.
Online-Abstract

Pfaller CK, Bloyet LM, Donohue RC, Huff AL, Bartemes WP, Yousaf I, Urzua E, Clavière M, Zachary M, de Masson d'Autume V, Carson S, Schieferecke AJ, Meyer AJ, Gerlier D, Cattaneo R (2020): The C Protein Is Recruited to Measles Virus Ribonucleocapsids by the Phosphoprotein.
J Virol 94: e01733-19.
Online-Abstract

Braun E, Hotter D, Koepke L, Zech F, Groß R, Sparrer KMJ, Müller JA, Pfaller CK, Heusinger E, Wombacher R, Sutter K, Dittmer U, Winkler M, Simmons G, Jakobsen MR, Conzelmann KK, Pöhlmann S, Münch J, Fackler OT, Kirchhoff F, Sauter D (2019): Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins.
Cell Rep 27: 2092-2104.e10.
Online-Abstract

Cattaneo R, Donohue RC, Generous AR, Navaratnarajah CK, Pfaller CK (2019): Stronger together: Multi-genome transmission of measles virus.
Virus Res 265: 74-79.
Online-Abstract

Singh BK, Pfaller CK, Cattaneo R, Sinn PL (2019): Measles Virus Ribonucleoprotein Complexes Rapidly Spread across Well-Differentiated Primary Human Airway Epithelial Cells along F-Actin Rings.
mBio 10: e02434-19.
Online-Abstract