The objective of the present non-interventional study is to observe the duration of clinical benefit from atezolizumab treatment in patients with locally-advanced or metastatic NSCLC of squamous or non-squamous histology after prior chemotherapy under real-world conditions. Furtermore, this NIS aims at investigating the association of previous therapies and patientes' baseline characteristics with the clinical benefit in atezolizumab-treated patients under real-world conditions.